Synthase
In biochemistry, a synthase is an enzyme that catalyses a synthesis process. Following the EC number classification, they belong to the group of lyases.
Note that, originally, biochemical nomenclature distinguished synthetases and synthases. Under the original definition, synthases do not use energy from nucleoside triphosphates (such as ATP, GTP, CTP, TTP, and UTP), whereas synthetases do use nucleoside triphosphates. However, the Joint Commission on Biochemical Nomenclature (JCBN) dictates that 'synthase' can be used with any enzyme that catalyzes synthesis (whether or not it uses nucleoside triphosphates), whereas 'synthetase' is to be used synonymously with 'ligase'.[1]
Examples
- ATP synthase
- Citrate synthase
- Tryptophan synthase
- Pseudouridine synthase
- Fatty acid synthase
- Cellulose synthase (UDP-forming)
- Cellulose synthase (GDP-forming)
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References
- "Archived copy". Archived from the original on 2012-10-15. Retrieved 2009-06-02.CS1 maint: archived copy as title (link)
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