Salicylanilide

Salicylanilide[1]
Names
	IUPAC name 2-Hydroxy-N-phenylbenzamide
	Other names 2-Hydroxybenzanilide
Identifiers
CAS Number	87-17-2 ;
3D model (JSmol)	Interactive image;
ChemSpider	6610 ;
ECHA InfoCard	100.001.571
PubChem CID	6872;
UNII	LHP8NEY345 ;
CompTox Dashboard (EPA)	DTXSID7021784 ;
	InChI InChI=1S/C13H11NO2/c15-12-9-5-4-8-11(12)13(16)14-10-6-2-1-3-7-10/h1-9,15H,(H,14,16) Key: WKEDVNSFRWHDNR-UHFFFAOYSA-N ; InChI=1/C13H11NO2/c15-12-9-5-4-8-11(12)13(16)14-10-6-2-1-3-7-10/h1-9,15H,(H,14,16) Key: WKEDVNSFRWHDNR-UHFFFAOYAI;
	SMILES C1=CC=C(C=C1)NC(=O)C2=CC=CC=C2O;
Properties
Chemical formula	C13H11NO2
Molar mass	213.236 g·mol−1
Appearance	White to off-white crystalline solid
Melting point	136 to 138 °C (277 to 280 °F; 409 to 411 K)
Hazards
EU classification (DSD) (outdated)	Xi
R-phrases (outdated)	R36/37/38
S-phrases (outdated)	S36/37/39
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references

Salicylanilide is a chemical compound which is the amide of salicylic acid and aniline. It is classified as both a salicylamide and an anilide.[2]

Derivatives of salicylanilide have a variety of pharmacological uses. Chlorinated derivatives including niclosamide, oxyclozanide, and rafoxanide are used as anthelmintics, especially as flukicides. Brominated derivatives including dibromsalan, metabromsalan, and tribromsalan are used as disinfectants with antibacterial and antifungal activities.

Uses

Salicylanilides may be used as antiseptics.
Replacement of the phenol with iodo leads to de:Benodanil, which is fungicidal.

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Salicylanilide at chemicalland21.com
Salicylanilides at the US National Library of Medicine Medical Subject Headings (MeSH)

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