Rafoxanide

Rafoxanide is a salicylanilide used as an anthelmintic.[1] It is most commonly used in ruminant animals to treat adult liver flukes of the species Fasciola hepatica and Fasciola gigantica.[1]

Rafoxanide
Names
IUPAC name
N-[3-Chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3,5-diiodobenzamide
Other names
Rafoxanid, raphoxanide
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.041.029
EC Number
  • 245-148-9
KEGG
MeSH D011888
UNII
Properties
C19H11Cl2I2NO3
Molar mass 626.01 g/mol
Appearance Slight yellowish-brown injectable solution and white oral solution
In oily solutes
Pharmacology
QP52AG05 (WHO)
Hazards
Main hazards Has low safety index (6 times as normal dose)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

References

  1. Lanusse, Carlos E.; Alvarez, Luis I.; Virkel, Guillermo L. (2018). "Chapter 40. Anticestodal and antitrematodal drugs. Rafoxanide". In Riviere, Jim E.; Papich, Mark G. (eds.). Veterinary Pharmacology and Therapeutics (10th ed.). John Wiley & Sons. p. 1091. ISBN 9781118855829.


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