Nebovirus

Nebovirus is a genus of viruses, in the family Caliciviridae[1]. Bovine serve as natural hosts. There is currently only one species in this genus: the type species Newbury-1 virus.[2] Diseases associated with this genus include: necrotizing hepatitis leading to fatal hemorrhages.[3]

Nebovirus
Virus classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Pisuviricota
Class: Pisoniviricetes
Order: Picornavirales
Family: Caliciviridae
Genus: Nebovirus
Type species
Newbury-1 virus

Taxonomy

Group: ssRNA(+)

[2]

Structure

Viruses in Nebovirus are non-enveloped, with icosahedral geometries, and T=3, T=1 symmetry. The diameter is around 35 nm. Genomes are linear and non-segmented, around 8.3kb in length.[3]

GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
NebovirusIcosahedralT=1, T=3Non-envelopedLinearMonopartite

Life cycle

Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment to host receptors, which mediates endocytosis. Replication follows the positive stranded RNA virus replication model. Positive stranded RNA virus transcription is the method of transcription. Translation takes place by RNA termination-reinitiation. Bovine serve as the natural host.[3]

GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
NebovirusBovineLiverCell receptor endocytosisLysisCytoplasmCytoplasmUnknown
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References
  1. Vinjé, J; Estes, MK; Esteves, P; Green, KY; Katayama, K; Knowles, NJ; L'Homme, Y; Martella, V; Vennema, H; White, PA; ICTV Report Consortium (November 2019). "ICTV Virus Taxonomy Profile: Caliciviridae". The Journal of General Virology. 100 (11): 1469–1470. doi:10.1099/jgv.0.001332. PMID 31573467.
  2. "ICTV Report Caliciviridae".
  3. "Viral Zone". ExPASy. Retrieved 13 August 2015.
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