Mupapillomavirus

Mupapillomavirus is a genus of viruses in the family Papillomaviridae.[1] Humans serve as natural hosts. There are currently three species in this genus, including the type species Mupapillomavirus 1. Diseases associated with this genus include palmoplantar warts.[2][3]

Mupapillomavirus
Virus classification
(unranked): Virus
Realm: Monodnaviria
Kingdom: Shotokuvirae
Phylum: Cossaviricota
Class: Papovaviricetes
Order: Zurhausenvirales
Family: Papillomaviridae
Genus: Mupapillomavirus
Type species
Mupapillomavirus 1

Taxonomy

Group: dsDNA

[3]

Structure

Viruses in Mupapillomavirus are non-enveloped, with icosahedral geometries, and T=7 symmetry. The diameter is around 52-55 nm. Genomes are circular, around 8kb in length.[2]

GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
MupapillomavirusIcosahedralT=7Non-envelopedCircularMonopartite

Life cycle

Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear envelope breakdown. Human serve as the natural host. Transmission routes are contact.[2]

GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
MupapillomavirusHumansEpithelial: mucous; epithelial: skinCell receptor endocytosisLysisNucleusNucleusContact
gollark: Maybe "things which go against previously received evidence" is more accurate than "counterintuitive things", but same principle.
gollark: > So does every source, yet I only ever run into this obsession with checking the sources in graphics when I present data that runs counter to whatever the prevailing narrative is...People want more confirmation for counterintuitive things.
gollark: https://discord.com/channels/424394851170385921/471334670483849216/763424360764538900
gollark: Their figures seem pretty good *now*.
gollark: Sweden seems to have done decently so far with just social distancing and more hygiene stuff, somehow.

References
  1. Van Doorslaer, K; Chen, Z; Bernard, HU; Chan, PKS; DeSalle, R; Dillner, J; Forslund, O; Haga, T; McBride, AA; Villa, LL; Burk, RD; ICTV Report Consortium (August 2018). "ICTV Virus Taxonomy Profile: Papillomaviridae". The Journal of General Virology. 99 (8): 989–990. doi:10.1099/jgv.0.001105. PMC 6171710. PMID 29927370.
  2. "Viral Zone". ExPASy. Retrieved 15 June 2015.
  3. "ICTV Report Papillomaviridae".
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