L-cysteate sulfo-lyase

In enzymology, a L-cysteate sulfo-lyase (EC 4.4.1.25) is an enzyme that catalyzes the chemical reaction

L-cysteate + H2O pyruvate + bisulfite + NH3
L-cysteate sulfo-lyase
Identifiers
EC number4.4.1.25
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Thus, the two substrates of this enzyme are L-cysteate and H2O, whereas its 3 products are pyruvate, bisulfite, and NH3.

This enzyme belongs to the family of lyases, specifically the class of carbon-sulfur lyases. The systematic name of this enzyme class is L-cysteate bisulfite-lyase (deaminating; pyruvate-forming). Other names in common use include L-cysteate sulfo-lyase (deaminating), and CuyA.

References

    • Denger K, Smits TH, Cook AM (2006). "L-cysteate sulpho-lyase, a widespread pyridoxal 5'-phosphate-coupled desulphonative enzyme purified from Silicibacter pomeroyi DSS-3(T)". Biochem. J. 394 (Pt 3): 657–64. doi:10.1042/BJ20051311. PMC 1383715. PMID 16302849.


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