Kappatorquevirus
Kappatorquevirus is a genus of viruses, in the family Anelloviridae. Pigs serve as natural hosts. There are currently two species in this genus including the type species Torque teno sus virus k2. Diseases associated with this genus include: possibly post-weaning multisystemic wasting syndrome (PMWS).[1][2]
Kappatorquevirus | |
---|---|
Virus classification | |
(unranked): | Virus |
Realm: | incertae sedis |
Kingdom: | incertae sedis |
Phylum: | incertae sedis |
Class: | incertae sedis |
Order: | incertae sedis |
Family: | Anelloviridae |
Genus: | Kappatorquevirus |
Type species | |
Torque teno sus virus k2a |
Taxonomy
Group: ssDNA
- Family: Anelloviridae
- Genus: Kappatorquevirus
- Torque teno sus virus k2a
- Torque teno sus virus k2b
Structure
Viruses in Kappatorquevirus are non-enveloped, with icosahedral geometries, and T=1 symmetry. The diameter is around 19-27 nm. Genomes are circular, around 2.7kb in length. The genome codes for 4 proteins, and has 3 open reading frames.[1]
Genus | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
---|---|---|---|---|---|
Kappatorquevirus | Icosahedral | T=1 | Non-enveloped | Circular | Monopartite |
Life cycle
Viral replication is nuclear. Entry into the host cell is achieved by penetration into the host cell. Replication follows the ssDNA rolling circle model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear pore export. Pigs serve as the natural host. Transmission routes are parental.[1]
Genus | Host details | Tissue tropism | Entry details | Release details | Replication site | Assembly site | Transmission |
---|---|---|---|---|---|---|---|
Kappatorquevirus | Pigs | None | Cell receptor endocytosis | Budding | Nucleus | Nucleus | Vertical; horizontal |
References
- "Viral Zone". ExPASy. Retrieved 13 August 2015.
- ICTV. "Virus Taxonomy: 2014 Release". Retrieved 13 August 2015.