Isovoacangine

Isovoacangine is a naturally occurring substance related to voacangine.It showed negative chronotropic and negative inotropic activity.[1]

Isovoacangine
Identifiers
PubChem CID
ChemSpider
ChEMBL
Chemical and physical data
FormulaC22H28N2O3
Molar mass368.477 g·mol−1
3D model (JSmol)

Uses

Medical

Pharmacology

Pharmacodynamics

Pharmacokinetics

Chemistry

Synthesis

Derivatives

3-Hydroxyisovoacangine and 3-(2'-oxopropyl)isovoacangine(formed by reaction with acetone) are derivates of isovoacangine.[2]

Natural occurrence

It occurs naturally in many Tabernaemontana (milkwood) species such as Tabernaemontana pachysiphon and Tabernaemontana_divaricata.[3][4]

Society and culture

Research

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See also

References

  1. Data. medind.nic.in (PDF) http://medind.nic.in/iby/t08/i4/ibyt08i4p317.pdf. Retrieved 2020-05-24. Missing or empty |title= (help)
  2. "The Alkaloids: Chemistry and Pharmacology". Academic Press. October 1, 1987 via Google Books.
  3. "Tabernaemontana undulata - Useful Tropical Plants". tropical.theferns.info.
  4. Kam, Toh-Seok; Loh, Kah-Yeng; Wei, Chen (November 1, 1993). "Conophylline and Conophyllidine: New Dimeric Alkaloids from Tabernaemontana divaricata". Journal of Natural Products. 56 (11): 1865–1871. doi:10.1021/np50101a001 via ACS Publications.
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