Iotapapillomavirus

Iotapapillomavirus is a genus of viruses, in the family Papillomaviridae[1]. Rodents serve as natural hosts. There are currently two species in this genus, including the type species Iotapapillomavirus 1. Diseases associated with this genus include: cutaneous lesions and benign skin tumours, such as papillomas and keratoacanthomas.[2][3]

Iotapapillomavirus
Virus classification
(unranked): Virus
Realm: Monodnaviria
Kingdom: Shotokuvirae
Phylum: Cossaviricota
Class: Papovaviricetes
Order: Zurhausenvirales
Family: Papillomaviridae
Genus: Iotapapillomavirus
Type species
Iotapapillomavirus 1

Taxonomy

Group: dsDNA

[3]

Structure

Viruses in Iotapapillomavirus are non-enveloped, with icosahedral geometries, and T=7 symmetry. The diameter is around 60 nm. Genomes are circular, around 8kb in length.[2]

GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
IotapapillomavirusIcosahedralT=7Non-envelopedCircularMonopartite

Life cycle

Viral replication is nuclear. Entry into the host cell is achieved by attachment of the viral proteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear envelope breakdown. Rodents serve as the natural host. Transmission routes are contact.[2]

GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
IotapapillomavirusRodentsEpithelial: mucous; epithelial: skinCell receptor endocytosisLysisNucleusNucleusContact
gollark: I don't see why endianness is a problem. GTech™ solved this ages ago with our per-value permutation system.
gollark: This probably does imply regular determinism.
gollark: Another is superdeterminism, which is sort of kind of where the particles "know" what properties of them will be measured in advance.
gollark: One resolution is nonlocal hidden variables, i.e. the particles have some faster-than-light-speed backchannel to communicate things.
gollark: Bell's theorem rules out "local hidden-variables" interpretations of quantum physics, meaning that quantum mechanics cannot, assuming some assumptions, be doing this by storing some extra secret metadata with particles.

References
  1. Van Doorslaer, K; Chen, Z; Bernard, HU; Chan, PKS; DeSalle, R; Dillner, J; Forslund, O; Haga, T; McBride, AA; Villa, LL; Burk, RD; ICTV Report Consortium (August 2018). "ICTV Virus Taxonomy Profile: Papillomaviridae". The Journal of General Virology. 99 (8): 989–990. doi:10.1099/jgv.0.001105. PMC 6171710. PMID 29927370.
  2. "Viral Zone". ExPASy. Retrieved 15 June 2015.
  3. "ICTV Report Papillomaviridae".
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