Indoleacetaldoxime dehydratase
In enzymology, an indoleacetaldoxime dehydratase (EC 4.99.1.6) is an enzyme that catalyzes the chemical reaction
- (indol-3-yl)acetaldehyde oxime (indol-3-yl)acetonitrile + H2O
| indoleacetaldoxime dehydratase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.99.1.6 | ||||||||
| CAS number | 9024-27-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Hence, this enzyme has one substrate, (indol-3-yl)acetaldehyde oxime, and two products, (indol-3-yl)acetonitrile and H2O.
This enzyme belongs to the family of lyases, specifically the "catch-all" class of lyases that do not fit into any other sub-class. The systematic name of this enzyme class is (indol-3-yl)acetaldehyde-oxime hydro-lyase [(indol-3-yl)acetonitrile-forming]. Other names in common use include indoleacetaldoxime hydro-lyase, 3-indoleacetaldoxime hydro-lyase, indole-3-acetaldoxime hydro-lyase, indole-3-acetaldehyde-oxime hydro-lyase, and (indol-3-yl)acetaldehyde-oxime hydro-lyase. This enzyme participates in cyanoamino acid metabolism.
References
- KUMAR SA, MAHADEVAN S (1963). "3-INDOLEACETALDOXIME HYDRO-LYASE: A PYRIDOXAL-5'-PHOSPHATE ACTIVATED ENZYME". Arch. Biochem. Biophys. 103 (3): 516–8. doi:10.1016/0003-9861(63)90446-6. PMID 14099566.
- Mahadevan S (1963). "Conversion of 3-indoleacetoxime to 3-indoleacetonitrile by plants". Arch. Biochem. Biophys. 100 (3): 557–558. doi:10.1016/0003-9861(63)90127-9.