Hederagenin

Hederagenin is a triterpenoid which is a chemical constituent of the Hedera helix plant.

Hederagenin
Names
IUPAC name
(3β)-3,23-Dihydroxyolean-12-en-28-oic acid
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.006.701
UNII
Properties
C30H48O4
Molar mass 472.710 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Hederagenin is the aglycone part of numerous saponins found in Hedera helix (common ivy), the most prevalent of these being hederacoside C and alpha-hederin. It is also one of three primary triterpenoids extracted from the Chenopodium quinoa plant categorized by the EPA as a biopesticide.[1] HeadsUp Plant Protectant is made up of approximately equal ratios of the saponin aglycones oleanolic acid, hederagenin, and phytolaccagenic acid and is intended for use as a seed treatment on tuber (e.g. potato seed pieces), legume, and cereal seeds or as a pre-plant root dip for roots of transplants, at planting, to prevent fungal growth, bacterial growth, and viral plant diseases.

Hederagenin has been found to have antidepressant-like effects in a rodent models.[2]

History

Hederagenin was discovered by L. Posselt in 1849 and named hederic acid.[3] However, Posselt was not able to isolate a pure substance or obtain an exact formula: his hederic acid was hederagenin mixed with some tannin impurity.[4]

All of these compounds share the same pentacyclic framework:

gollark: Also, it really should be capable of searching a few hundred thousand nodes and JS is clearly just being hilariously inefficient, but if I use WASM I could write a better Rust implementation.
gollark: *But* I could probably make it pick positions based on a heuristic to maximize the amount of nearly-lines it has and to minimize the opponent's.
gollark: So the initial simple minimax thing didn't work well because it couldn't search deep trees because combinatorial explosion.
gollark: Which I guess would come under "more computing resources". But anyway.
gollark: Anyway, I *did* have an idea to make the AI work better without substantially more computing resources or accursed neural network™ things.

References
  1. BIOPESTICIDES REGISTRATION ACTION DOCUMENT, Saponins of Chenopodium quinoa.
  2. Zhou, D; Jin, H; Lin, HB; Yang, XM; Cheng, YF; Deng, FJ; Xu, JP (2010). "Antidepressant effect of the extracts from Fructus Akebiae". Pharmacology Biochemistry and Behavior. 94 (3): 488–95. doi:10.1016/j.pbb.2009.11.003. PMID 19931301.
  3. L. Posselt, "On the constituents of the seeds of ivy", Liebig's Annalen der Chemie, January 1849.
  4. John Lionel Simonsen, The Terpenes, p. 174, Cambridge University Press, 1947 OCLC 309782.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.