GRAMD1C

GRAM domain containing 1C also known as Aster-C is a protein that is encoded by the GRAMD1C gene.[3][4] It contains a transmembrane region, a GRAM domain and a VASt domain.

GRAMD1C
Identifiers
Aliases	GRAMD1C, GRAM domain containing 1C
External IDs	HomoloGene: 9726 GeneCards: GRAMD1C
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3q13.31 Start 113,828,182 bp[1] End 113,947,174 bp[1]
Gene ontology Molecular function • GO:0001948 protein binding • cholesterol binding • GO:0017127 cholesterol transfer activity • lipid binding Cellular component • membrane • integral component of membrane • endoplasmic reticulum membrane • cell membrane • endoplasmic reticulum-plasma membrane contact site • endoplasmic reticulum Biological process • cholesterol transport • cellular response to cholesterol • intermembrane sterol transfer • lipid transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	54762	n/a
Ensembl	ENSG00000178075	n/a
UniProt	Q8IYS0	n/a
RefSeq (mRNA)	NM_001172105 NM_017577	n/a
RefSeq (protein)	NP_001165576 NP_060047	n/a
Location (UCSC)	Chr 3: 113.83 – 113.95 Mb	n/a
PubMed search	[2]	n/a
Wikidata
View/Edit Human

GRAMD1C has four paralogs: GRAMD1B and GRAMD1A and two without VASt domains, GRAMD2A and GRAMD2B.

References

1. GRCh38: Ensembl release 89: ENSG00000178075 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: GRAM domain containing 1C". Retrieved 2018-10-17.
4. "UniProtKB - Q8IYS0 (ASTRC_HUMAN)". Retrieved March 6, 2020.