Etofamide

Etofamide (INN, also known as eticlordifene) is an antiprotozoal drug used in the treatment of amoebiasis.

Etofamide

Clinical data
AHFS/Drugs.com	International Drug Names
Routes of administration	Oral
ATC code	P01AC03 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name 2,2-dichloro-N-(2-ethoxyethyl)-N- [4-(4-nitrophenoxy)benzyl]acetamide
CAS Number	25287-60-9^Y
PubChem CID	65718
ChemSpider	59142
UNII	03F36JH21U
KEGG	D07355^Y
ChEMBL	ChEMBL1788393
CompTox Dashboard (EPA)	DTXSID40179926
ECHA InfoCard	100.042.522
Chemical and physical data
Formula	C19H20Cl2N2O5
Molar mass	427.28 g·mol^−1
3D model (JSmol)	Interactive image
SMILES CCOCCN(CC1=CC=C(C=C1)OC2=CC=C(C=C2)[N+](=O)[O-])C(=O)C(Cl)Cl
InChI InChI=1S/C19H20Cl2N2O5/c1-2-27-12-11-22(19(24)18(20)21)13-14-3-7-16(8-4-14)28-17-9-5-15(6-10-17)23(25)26/h3-10,18H,2,11-13H2,1H3 Key:QTRALMGDQMIVFF-UHFFFAOYSA-N
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Its effect against Giardia lamblia has been described as modest.[1]

References

1. Cedillo-Rivera R, Muñoz O (September 1992). "In-vitro susceptibility of Giardia lamblia to albendazole, mebendazole and other chemotherapeutic agents". Journal of Medical Microbiology. 37 (3): 221–4. doi:10.1099/00222615-37-3-221. PMID 1518040.