Elad Levy


Elad I. Levy is an American neurosurgeon, researcher, and innovator who played a major role in the development and testing of thrombectomy,[1] which improved quality of life and survival of stroke patients. He has focused his career and research on developing evidence based medicine and literature showing the benefits of thrombectomy for the treatment of stroke. He is currently Professor of Neurosurgery and Radiology, and the L. Nelson Hopkins, MD Professor Endowed Chair of the Department of Neurosurgery at the State University of New York at Buffalo (SUNY).[2][3]

Elad I. Levy
Born (1972-08-29) August 29, 1972
Tiberias, Israel
NationalityAmerican and Israeli
CitizenshipUSA and Israel
EducationDartmouth College (1993), George Washington University School of Medicine(1997), Northeastern University (2013)
Known forEndovascular neurology, stroke intervention
Scientific career
FieldsNeurosurgery
InstitutionsState University of New York at Buffalo
Websitewww.ubns.com, medicine.buffalo.edu,

Twitter: twitter.com/eladlevymd?lang=en,

Instagram: www.instagram.com/eladlevymd/

In 2011 Levy founded and is currently the president for the Program for Understanding Childhood Concussion & Stroke (PUCCS), to date this organization has raised over $750,000 which is aimed towards promoting research and preventing concussions in all sports.[4] In 2013 he became the unaffiliated National Football League (NFL) Neurotrauma consultant for the Buffalo Bills.[5] In 2017 he was appointed as one of 12 National Directors to the American Board of Neurological Surgeons.[6] In 2018 he was appointed Secretary to the Congress of Neurological Surgeons Executive Committee [7] and also appointed to the Ethics Committee for the American Association of Neurological Surgeons.[8] He is also the Director of Stroke Research and Director of Endovascular Stroke Treatment and Research at the Department of Neurosurgery, SUNY at Buffalo, Co-Director of Kaleida Health Stroke Center at the Gates Vascular Institute, and Co-Director of Cerebrovascular Surgery at the Department of Neurosurgery, SUNY at Buffalo.[9] In 2020 Levy received his appointment as Distinguished Professor at the State University of New York at Buffalo due to his prolific contributions to research, innovation, leadership and academia.[10]

Early life and education

Levy was born in Tiberias, Israel in 1972. His father went to medical school in Italy, where Dr. Levy learned to speak Italian, in addition to English in school and Hebrew at home. At the age of seven, he immigrated to the United States. After his father's residency training in obstetrics and gynecology in New York City, his family settled in rural northern upstate New York close to Montreal, where his dad joined a solo Obstetrics and gynecology practice. Growing up, Levy spent his summers with his father's family in Israel. Dr. Levy went onto attend local schools before his last two years of High School, which he spent at Choate Rosemary Hall, a private boarding school in Wallingford, Connecticut.

Athletic career

During his time at Choate Rosemary Hall he became interested in rowing, which eventually became his passion and earned him a roster spot on the Division I rowing team at Darthmouth College where he was an oarsman between the years 1989–1993. During this time he also won 2 gold medals at the Maccabiah Games in 1990 and joined the U.S. Junior National Rowing team in 1991. He was also awarded the Woodhead award for grit. Dr. Levy also frequently takes part in marathons and half iron man competitions across the country.[11]

Higher education and training

Levy went to Dartmouth College to study molecular biology and biochemistry. He began medical school in 1993 at The George Washington University School of Medicine & Health Sciences in Washington, D.C.,[9] where he became interested in Orthopedic Surgery. However, when he did not secure the summer orthopedic internship after his freshman year, he chose to do a summer research project with Dr. Laligam Sekhar, the Chairman of Neurosurgery at George Washington University at the time, since then neurosurgery became his focus.[12]

Following graduation in 1997, Levy began his surgical internships and training in neurosurgery at the University of Pittsburgh, one of the highest volume programs in the country. As a young intern, he quickly learned the importance of innovation and the obligation to push the field forward for better care of neurosurgical patients. Following in the footsteps of Dr. Peter Jannetta, the “father of microvascular decompression,” and Dr. Dade Lunsford, who introduced Gamma-knife radiosurgery to the University of Pittsburgh, Levy pursued minimally invasive endovascular neurosurgery by spending 2 years of his residency in Buffalo, as a fellow under Dr. L. Nelson Hopkins, the “father of neurointerventional surgery".[12] He completed his fellowship training in 2003 and returned to Pittsburgh to finish his residency training in 2004.[13]

In later years, Levy also completed his Master of Business Administration at Northeastern University and graduated magna cum laude in 2013.[9]

Academic and professional career

Levy started his academic and professional career as an Associate Professor of Neurosurgery and Radiology at the State University of New York (SUNy) at Buffalo in 2004. The following year in 2005, he became the Director for Stroke Research, and Co-Director of Cerebrovascular Surgery at the Department of Neurosurgery, SUNY at Buffalo. He was also appointed as Co-Director of Kaleida Health Stroke Center and the Director of Endovascular Stroke Treatment and Research in 2006. He also served as the Endovascular Fellowship Program Director for the Department of Neurosurgery, SUNY at Buffalo from 2006 to 2013.

In 2010, Levy was promoted to the title of Professor of Neurosurgery and Radiology becoming one of the youngest tenured professors in the SUNY system.[14] Subsequently, in 2013 when Dr. L. Nelson Hopkins retired as the Chair of Neurosurgery, Levy rapidly emerged as the top candidate among several candidates across the nation, demonstrating the administrative, scientific, clinical, leadership and visionary skills necessary for the growth of the department.[3] Since becoming the Chairman at University at Buffalo, Neurosurgery, Levy has recruited some of the best trained young neurosurgeons and more than doubled the size of the faculty. Leading by example, he promoted the academic productivity of the department, which secured a top 5 ranking for endovascular neurosurgery.[15]

Levy served as an invited Guest Examiner for Oral Examinations for the American Board of Neurosurgeons in 2014, 2016, 2017, and in 2018 became Director. He has trained several physicians from all around the globe, and chaired the 2014 Scientific Program and the 2015 Annual Meeting of the Congress of Neurological Surgeons.[16]

Selected awards and recognitions
  • 2020: Distinguished Professor at State University of New York at Buffalo [10]
  • 2020: Power 250 Award By Buffalo Business First [17]
  • 2019: Buffalo Business First Excellence in Health Care Award [18]
  • 2018: Awarded the prestigious Drake Lectureship at the Congress of Neurological Surgeons [19]
  • 2018 : "Teacher of the year Award" recognized by Residents and Fellows at the University at Buffalo Neurosurgery for dedication to teaching and mentoring, given by the Department of Family Medicine, Jacobs School of Medicine and Biomedical Sciences
  • 2017: Buffalo Business First “Power 250 Award” for most influential business and community leaders[20]
  • 2016: Recipient of the L. Nelson Hopkins, MD Professor and Endowed Chair of Neurosurgery Award
  • 2015: The George Washington University “Distinguished Alumni Achievement Award” for special recognition of professional accomplishments. The “Distinguished Alumni Achievement Award” is one of the most prestigious honors bestowed by the University[21]
  • 2014: State University of New York “Chancellor’s Award” for Excellence in Scholarship and Creative Activities[22]
  • 2014: Recipient of the “2014 Hero of the Heart” Award for the American Heart Association in Western New York. Recognized as a “world renowned physician’. Given to community members who help spread the American Heart Association's lifesaving mission[23]
  • 2012: Winner of the George Thorn Young Investigator Award from University at Buffalo School of Medicine[24]

Research

Levy has helped develop and perfect the endovascular treatment modalities for stroke. His research work focuses on neurovascular diseases such as stroke, brain aneurysms and vessel malformations. He has published and lectured extensively on the endovascular techniques for cerebrovascular disorders,[25] including more than 350 peer-reviewed publications and more than 200 book chapters.[26][27] He has also contributed several live cases for national and international meetings as well as for community education.[28]

He has been involved with research resulting in paradigm shifts in the treatment of cerebrovascular diseases, including being the US Interventional Principal Investigator for the SWIFT PRIME trials.[29] Levy's research work holds an H-index of 81.[30]

Selected publications

A partial list of articles is provided below:

  • Thrombectomy 6 to 24 Hours after Stroke with Mismatch between Deficit and Infarct[31]
  • Safety and Efficacy of a 3-Dimensional Stent Retriever With Aspiration-Based Thrombectomy vs Aspiration-Based Thrombectomy Alone in Acute Ischemic Stroke Intervention: A Randomized Clinical Trial[32]
  • Results of the ANSWER Trial using the PulseRider for the Treatment of Broad-Necked, Bifurcation Aneurysms[33]
  • Long-Term Clinical and Angiographic Outcomes Following Pipeline Embolization Device Treatment of Complex Internal Carotid Artery Aneurysms: Five-Year Results of the Pipeline for Uncoilable or Failed Aneurysms Trial[34]
  • Endovascular Thrombectomy After Large-Vessel Ischaemic Stroke: A Meta-Analysis of Individual Patient Data from Five Randomised Trials[35]
  • Safety and Efficacy of Solitaire Stent Thrombectomy: Individual Patient Data Meta-analysis of Randomized Trials[35]
  • Stent-Retriever Thrombectomy after Intravenous t-PA vs. t-PA Alone in Stroke[36]
  • Aggressive Medical Treatment With or Without Stenting in High-risk Patients with Intracranial Artery Stenosis (SAMMPRIS): The Final Results of a Randomised Trial[37]
  • Pipeline for Uncoilable or Failed Aneurysms: Results from a Multicenter Clinical Trial[38]
  • Solitaire Flow Restoration Device versus the Merci Retriever in Acute Ischaemic Stroke (SWIFT): A Randomized, Parallel-Group, Non-Inferiority Trial[39]
  • Stenting versus Aggressive Medical Therapy for Intracranial Arterial Stenosis[40]
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References
  1. Saver, Jeffrey L.; Goyal, Mayank; Bonafe, Alain; Diener, Hans-Christoph; Levy, Elad I.; Pereira, Vitor M.; Albers, Gregory W.; Cognard, Christophe; Cohen, David J.; Hacke, Werner; Jansen, Olav; Jovin, Tudor G.; Mattle, Heinrich P.; Nogueira, Raul G.; Siddiqui, Adnan H.; Yavagal, Dileep R.; Baxter, Blaise W.; Devlin, Thomas G.; Lopes, Demetrius K.; Reddy, Vivek K.; Du Mesnil De Rochemont, Richard; Singer, Oliver C.; Jahan, Reza; SWIFT PRIME Investigators (June 11, 2015). "Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke" (PDF). The New England Journal of Medicine. 372 (24): 2285–2295. doi:10.1056/NEJMoa1415061. PMID 25882376.
  2. https://www.bizjournals.com/buffalo/print-edition/2013/09/20/young-and-poised-to-lead.html
  3. "UB medical school appoints Levy new chair of the Department of Neurosurgery". www.buffalo.edu.
  4. "PUCCS - Program for the Understanding of Childhood Concussion and Stroke". www.puccs.org.
  5. https://www.pittmed.health.pitt.edu/sites/default/files/alumni_summer2018.pdf
  6. "Leadership". American Board of Neurological Surgery.
  7. "Executive Committee". www.cns.org. March 13, 2014.
  8. "AANS Committees and Committee Members". www.aans.org.
  9. "Faculty Profile". medicine.buffalo.edu.
  10. http://www.buffalo.edu/ubnow/stories/2020/04/suny-distinguished-profs.html?fbclid=IwAR1_uPy9T7Q1ieJXx4mEve0sboyHp-sNPo3c4imYdwUfXI6g2d3uvlTB8kg
  11. "Dr. Elad Levy | Orthopedics This Week". ryortho.com. Retrieved 2019-06-07.
  12. "Dr. Elad Levy | Orthopedics This Week". ryortho.com.
  13. "Physician Profile". ubmd.com.
  14. Wood, Megan. "George Washington University honors Dr. Elad Levy alumni achievement award: 5 highlights". www.beckersspine.com.
  15. Siddiqui, Adnan H.; Shakir, Hakeem J.; Levy, Bennett R.; Shallwani, Hussain; Sonig, Ashish (January 13, 2017). "Academic impact and rankings of neuroendovascular fellowship programs across the United States". Journal of Neurosurgery. 127 (5): 1181–1189. doi:10.3171/2016.9.JNS161857. PMID 28084907.
  16. https://www.societyns.org/society/bio.aspx?MemberID=156934
  17. https://www.bizjournals.com/buffalo/news/2020/02/11/power-250-it-s-kickoff-time-for-the-8th-annual.html?iana=hpmvp_buff_news_headline?ana=e_buff_bn_breakingnews&j=90473311&t=Breaking%20News&mkt_tok=eyJpIjoiTUdNMk1EWmtZVFJqTXpNMiIsInQiOiJuTHBwUnNJTmNIazd3S0RQNE9Jb0ltU2EwdlM0NXBWQlJMaXA4SG5DK0pGS3VCV3RiQVwvamk5YUFadWJCcFBxcDNvdVFSeDBCVUpWSGsyak8xeVRZMG02UzZKVUlrZ2kzS0VIeHFJQnJDNFpPUFJZUEliZ1RiZWZ0eWRtY3ZhYlYifQ%3D%3D
  18. https://www.bizjournals.com/buffalo/news/2019/02/06/event-to-honor-25-health-care-professionals.html
  19. Barry, Kathy (May 29, 2018). "Section on Cerebrovascular Surgery Session 1". www.cns.org.
  20. "2017 Power 250 Winners Announced – Kaleida Health – Buffalo, NY". m.kaleidahealth.org.
  21. "SMHS Alumnus Receives Award for Contributions to Stroke Research | The School of Medicine & Health Sciences". smhs.gwu.edu.
  22. "20 receive Chancellor's Awards". www.buffalo.edu.
  23. "Dr. Elad Levy and Dr. Vernice Bates Named 'Hero of the Heart' Recipients – Western NY". westernny.heart.org.
  24. Copland, Nicky (February 10, 2017). "Shekar Kurpad, MD, PhD, and Elad Levy, MD, Elected to Executive Committee of the Congress of Neurological Surgeons". www.cns.org.
  25. "Elad Levy M.D.: Executive Profile & Biography - Bloomberg". www.bloomberg.com.
  26. "Thieme Medical Publishers - Elad I. Levy". www.thieme.com.
  27. "elad levy - PubMed - NCBI". www.ncbi.nlm.nih.gov.
  28. "Watching Life-Saving Stroke Procedures in Real Time at GVI". 2018-06-28.
  29. Saver, Jeffrey L.; Goyal, Mayank; Bonafe, Alain; Diener, Hans-Christoph; Levy, Elad I.; Pereira, Vitor M.; Albers, Gregory W.; Cognard, Christophe; Cohen, David J.; Hacke, Werner; Jansen, Olav; Jovin, Tudor G.; Mattle, Heinrich P.; Nogueira, Raul G.; Siddiqui, Adnan H.; Yavagal, Dileep R.; Baxter, Blaise W.; Devlin, Thomas G.; Lopes, Demetrius K.; Reddy, Vivek K.; Du Mesnil De Rochemont, Richard; Singer, Oliver C.; Jahan, Reza (2015). "Stent-Retriever Thrombectomy after Intravenous t-PA vs. T-PA Alone in Stroke" (PDF). New England Journal of Medicine. 372 (24): 2285–2295. doi:10.1056/NEJMoa1415061. PMID 25882376.
  30. "Elad I. Levy - Google Scholar Citations". scholar.google.com.
  31. Chow, Y. W.; Pietranico, R.; Mukerji, A. (1975). "Studies of oxygen binding energy to hemoglobin molecule". Biochemical and Biophysical Research Communications. 66 (4): 1424–31. doi:10.1016/0006-291x(75)90518-5. PMID 6.
  32. Nogueira RG, Frei D, Kirmani JF, et al. (March 1, 2018). "Safety and Efficacy of a 3-Dimensional Stent Retriever With Aspiration-Based Thrombectomy vs Aspiration-Based Thrombectomy Alone in Acute Ischemic Stroke Intervention: A Randomized Clinical Trial". JAMA Neurology. 75 (3): 304–311. doi:10.1001/jamaneurol.2017.3967. PMC 5885851. PMID 29296999.
  33. Spiotta, Alejandro M.; Derdeyn, Colin P.; Tateshima, Satoshi; Mocco, Jay; Crowley, R. Webster; Liu, Kenneth C.; Jensen, Lee; Ebersole, Koji; Reeves, Alan; Lopes, Demetrius K.; Hanel, Ricardo A.; Sauvageau, Eric; Duckwiler, Gary; Siddiqui, Adnan; Levy, Elad; Puri, Ajit; Pride, Lee; Novakovic, Roberta; Chaudry, M. Imran; Turner, Raymond D.; Turk, Aquilla S. (July 1, 2017). "Results of the ANSWER Trial Using the PulseRider for the Treatment of Broad-Necked, Bifurcation Aneurysms". Neurosurgery. 81 (1): 56–65. doi:10.1093/neuros/nyx085. PMID 28449126.
  34. Becske, Tibor; Brinjikji, Waleed; Potts, Matthew B.; Kallmes, David F.; Shapiro, Maksim; Moran, Christopher J.; Levy, Elad I.; McDougall, Cameron G.; Szikora, István; Lanzino, Giuseppe; Woo, Henry H.; Lopes, Demetrius K.; Siddiqui, Adnan H.; Albuquerque, Felipe C.; Fiorella, David J.; Saatci, Isil; Cekirge, Saruhan H.; Berez, Aaron L.; Cher, Daniel J.; Berentei, Zsolt; Marosfoi, Miklós; Nelson, Peter K. (January 1, 2017). "Long-Term Clinical and Angiographic Outcomes Following Pipeline Embolization Device Treatment of Complex Internal Carotid Artery Aneurysms: Five-Year Results of the Pipeline for Uncoilable or Failed Aneurysms Trial". Neurosurgery. 80 (1): 40–48. doi:10.1093/neuros/nyw014. PMID 28362885.
  35. Goyal, Mayank; Menon, Bijoy K.; Van Zwam, Wim H.; Dippel, Diederik W J.; Mitchell, Peter J.; Demchuk, Andrew M.; Dávalos, Antoni; Majoie, Charles B L M.; Van Der Lugt, Aad; De Miquel, Maria A.; Donnan, Geoffrey A.; Roos, Yvo B W E M.; Bonafe, Alain; Jahan, Reza; Diener, Hans-Christoph; Van Den Berg, Lucie A.; Levy, Elad I.; Berkhemer, Olvert A.; Pereira, Vitor M.; Rempel, Jeremy; Millán, Mònica; Davis, Stephen M.; Roy, Daniel; Thornton, John; Román, Luis San; Ribó, Marc; Beumer, Debbie; Stouch, Bruce; Brown, Scott; et al. (April 23, 2016). "Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials". Lancet. 387 (10029): 1723–1731. doi:10.1016/S0140-6736(16)00163-X. PMID 26898852 – via PubMed.
  36. Saver, Jeffrey L.; Goyal, Mayank; Bonafe, Alain; Diener, Hans-Christoph; Levy, Elad I.; Pereira, Vitor M.; Albers, Gregory W.; Cognard, Christophe; Cohen, David J.; Hacke, Werner; Jansen, Olav; Jovin, Tudor G.; Mattle, Heinrich P.; Nogueira, Raul G.; Siddiqui, Adnan H.; Yavagal, Dileep R.; Baxter, Blaise W.; Devlin, Thomas G.; Lopes, Demetrius K.; Reddy, Vivek K.; Du Mesnil De Rochemont, Richard; Singer, Oliver C.; Jahan, Reza (June 11, 2015). "Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke". The New England Journal of Medicine. 372 (24): 2285–2295. doi:10.1056/NEJMoa1415061. PMID 25882376 – via PubMed.
  37. Derdeyn CP, Chimowitz MI, Lynn MJ, Fiorella D, Turan TN, Janis LS, et al. (January 25, 2014). "Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial". Lancet. 383 (9914): 333–341. doi:10.1016/S0140-6736(13)62038-3. PMC 3971471. PMID 24168957.
  38. Becske, Tibor; Kallmes, David F.; Saatci, Isil; McDougall, Cameron G.; Szikora, István; Lanzino, Giuseppe; Moran, Christopher J.; Woo, Henry H.; Lopes, Demetrius K.; Berez, Aaron L.; Cher, Daniel J.; Siddiqui, Adnan H.; Levy, Elad I.; Albuquerque, Felipe C.; Fiorella, David J.; Berentei, Zsolt; Marosfoi, Miklós; Cekirge, Saruhan H.; Nelson, Peter K. (June 7, 2013). "Pipeline for uncoilable or failed aneurysms: results from a multicenter clinical trial". Radiology. 267 (3): 858–868. doi:10.1148/radiol.13120099. PMID 23418004.
  39. Saver, Jeffrey L.; Jahan, Reza; Levy, Elad I.; Jovin, Tudor G.; Baxter, Blaise; Nogueira, Raul G.; Clark, Wayne; Budzik, Ronald; Zaidat, Osama O.; SWIFT Trialists (October 6, 2012). "Solitaire flow restoration device versus the Merci Retriever in patients with acute ischaemic stroke (SWIFT): a randomised, parallel-group, non-inferiority trial". Lancet. 380 (9849): 1241–1249. doi:10.1016/S0140-6736(12)61384-1. PMID 22932715 – via PubMed.
  40. Chimowitz MI, Lynn MJ, Derdeyn CP, Turan TN, Fiorella D, Lane BF, et al. (September 15, 2011). "Stenting versus aggressive medical therapy for intracranial arterial stenosis". The New England Journal of Medicine. 365 (11): 993–1003. doi:10.1056/NEJMoa1105335. PMC 3552515. PMID 21899409.
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