Deacetylisoipecoside synthase
In enzymology, a deacetylisoipecoside synthase (EC 4.3.3.3) is an enzyme that catalyzes the chemical reaction
- deacetylisoipecoside + H2O dopamine + secologanin
| deacetylisoipecoside synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.3.3.3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are deacetylisoipecoside and H2O, whereas its two products are dopamine and secologanin.
This enzyme belongs to the family of lyases, specifically amine lyases, which cleave carbon-nitrogen bonds. The systematic name of this enzyme class is deacetylisoipecoside dopamine-lyase (secologanin-forming). This enzyme is also called deacetylisoipecoside dopamine-lyase. This enzyme participates in indole and ipecac alkaloid biosynthesis.
References
- De-Eknamkul W, Ounaroon A, Tanahashi T, Kutchan TM, Zenk MH (1997). "Enzymatic condensation of dopamine and secologanin by cell-free extracts of Alangium lamarckii". Phytochemistry. 45 (3): 477–484. doi:10.1016/S0031-9422(96)00828-X.
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