DDT-dehydrochlorinase
In enzymology, a DDT-dehydrochlorinase (EC 4.5.1.1) is an enzyme that catalyzes the chemical reaction
| DDT-dehydrochlorinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.5.1.1 | ||||||||
| CAS number | 9031-20-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene + chloride
Hence, this enzyme has one substrate, 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane, and two products, 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene and chloride.
This enzyme belongs to the family of lyases, specifically the class of carbon-halide lyases. The systematic name of this enzyme class is 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase [1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene-forming]. Other names in common use include DDT-ase, 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase, dehydrohalogenase, and DDTase. This enzyme participates in 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) and .
References
- LIPKE H, KEARNS CW (1959). "DDT dehydrochlorinase. I. Isolation, chemical properties, and spectrophotometric assay". J. Biol. Chem. 234 (8): 2123–8. PMID 13673024.
- LIPKE H, KEARNS CW (1959). "DDT dehydrochlorinase. II. Substrate and cofactor specificity". J. Biol. Chem. 234 (8): 2129–32. PMID 13673025.
- Moorefield HH (1956). "Purification of DDT-dehydrochlorinase from resistant houseflies". Contr. Boyce Thompson Inst. 18: 303–310.
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