DCrk

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Structures	Swiss-model
Domains	InterPro

Crk oncogene
Identifiers
Organism	Drosophila melanogaster
Symbol	Crk
UniProt	Q95RW2
Search for
Structures	Swiss-model
Domains	InterPro

DCrk (Drosophila ortholog of Crk) is the Drosophila melanogaster ortholog of the mammalian proteins Crk and CrkL.[1]

Structure and function

DCrk includes one SH2 domain followed by two SH3 domains and interacts with the MyoBlast City (MCB) protein. The DCrk protein is expressed during embryogenesis, declines during the larval stages, and reappears during pupation which suggests that DCrk plays an important role in development.[1]

gollark: Oh, it needs the debug API to be enabled for superglobals to work, ish.

gollark: It's HTTP-based.

gollark: Yes.

gollark: No, superglobals. They're more global.

gollark: Also, you can contribute code to it. Just send me random bits of code you like and I'll put them in somewhere.

References

Galletta BJ, Niu XP, Erickson MR, Abmayr SM (March 1999). "Identification of a Drosophila homologue to vertebrate Crk by interaction with MBC". Gene. 228 (1–2): 243–52. doi:10.1016/S0378-1119(99)00010-4. PMID 10072777.

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[pmid10072777-1] Galletta BJ, Niu XP, Erickson MR, Abmayr SM (March 1999). "Identification of a Drosophila homologue to vertebrate Crk by interaction with MBC". Gene. 228 (1–2): 243–52. doi:10.1016/S0378-1119(99)00010-4. PMID 10072777.