Cyanopeptolin

Cyanopeptolins are a class of oligopeptides produced by Microcystis and Planktothrix algae strains, and can be neurotoxic.[1][2][3] The production of cyanopeptolins occurs through nonribosomal peptides synthases (NRPS).[4]

Characteristics

Increased water temperatures, because of climate change and eutrophication of inland waters promote blooms of cyanobacteria, potentially threaten water contamination by the production of the toxic cyanopeptolin (CP1020).[1]

Exposure

Cyanopeptolin (CP1020) exposure in zebrafish affected pathways related to DNA damage, the circadian rhythm and response to light.[1]

gollark: At the extreme end, just iterate through... all ASCII descriptions of them, or something.
gollark: You totally could.
gollark: Just buy some GPU time off AWS or whatever and run a lot of them in parallel.
gollark: Well, the palaiologos neural networks can do it.
gollark: Well, if you just go through all possible human-runnable text "encryption" methods, you're bound to hit the right one eventually!

See also

References
  1. Susanne Faltermann, Sara Zucchi, Esther Kohler, Judith F. Blom, Jakob Pernthaler, Karl Fent (April 2014). "Molecular effects of the cyanobacterial toxin cyanopeptolin (CP1020) occurring in algal blooms: Global transcriptome analysis in zebrafish embryos". Aquatic Toxicology. 149: 33–39. doi:10.1016/j.aquatox.2014.01.018. PMID 24561424.CS1 maint: uses authors parameter (link)
  2. Karl Gademann, Cyril Portmann, Judith F. Blom, Michael Zeder and Friedrich Jüttner (2010). "Multiple Toxin Production in the Cyanobacterium Microcystis: Isolation of the Toxic Protease Inhibitor Cyanopeptolin 1020" (PDF). J. Nat. Prod. 73 (5): 980–984. doi:10.1021/np900818c. PMID 20405925.CS1 maint: uses authors parameter (link)
  3. Martin Welker and Hans Von Döhren (2006). "Cyanobacterial peptides – Nature's own combinatorial biosynthesis". FEMS Microbiology Reviews. 30 (4): 530–563. doi:10.1111/j.1574-6976.2006.00022.x. PMID 16774586.CS1 maint: uses authors parameter (link)
  4. Ramsy Agha, Samuel Cirés, Lars Wörmer and Antonio Quesada (2013). "Limited Stability of Microcystins in Oligopeptide Compositions of Microcystis aeruginosa (Cyanobacteria): Implications in the Definition of Chemotypes". Toxins. 5 (6): 1089–1104. doi:10.3390/toxins5061089. PMC 3717771. PMID 23744054.CS1 maint: uses authors parameter (link)
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.