Caldoramide

Caldoramide is a pentapeptide[1] isolated from the cyanobacteria Caldora penicillata. It has cytotoxic effects on cancer cells and has been the subject of extensive oncological research.[2]

Caldoramide

Identifiers
CAS Number	1961308-67-7
3D model (JSmol)	Interactive image
PubChem CID	132525321
InChI InChI=1S/C37H59N5O6/c1-22(2)19-28(35(45)42-27(29(48-13)21-30(42)43)20-26-17-15-14-16-18-26)40(11)37(47)33(25(7)8)41(12)36(46)31(23(3)4)38-34(44)32(24(5)6)39(9)10/h14-18,21-25,27-28,31-33H,19-20H2,1-13H3,(H,38,44)/t27-,28-,31-,32-,33-/m0/s1 Key: XMIMMOXGNBQXIJ-VLQZMBLPSA-N
SMILES CC(C)CC(C(=O)N1C(C(=CC1=O)OC)CC2=CC=CC=C2)N(C)C(=O)C(C(C)C)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)N(C)C
Properties
Chemical formula	C37H59N5O6
Molar mass	669.908 g·mol^−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References

1. Wunder, Anja; Rothemund, Matthias; Schobert, Rainer (2018). "Synthesis and anticancer activity of the proposed structure of caldoramide, an N-peptidyltetramate from the cyanobacterium Caldora penicillata". Tetrahedron. doi:10.1016/j.tet.2018.04.004.
2. Gunasekera, Sarath P; Imperial, Lorelie; Garst, Christiana; Ratnayake, Ranjala; Dang, Long H; Paul, Valerie J; Luesch, Hendrik (2016). "Caldoramide, a Modified Pentapeptide from the Marine Cyanobacterium Caldora penicillata". Journal of Natural Products. 79 (7): 1867–71. doi:10.1021/acs.jnatprod.6b00203. PMC 5215049. PMID 27380142.