Chris Goodnow

Christopher Carl Goodnow (born 19 September 1959) is an immunology researcher and the current Executive Director of the Garvan Institute of Medical Research. He holds the Bill and Patricia Ritchie Foundation Chair and is a Conjoint Professor in the Faculty of Medicine at UNSW Sydney. He holds dual Australian and US citizenship.

Chris Goodnow

FAA, FRS
Born
Hong Kong
Alma mater
Scientific career
Institutions

Career

Born in Hong Kong in 1959 to Robert Goodnow and Jacqueline J. Goodnow AC, Goodnow grew up in Rome and Washington DC before moving to Sydney, Australia as a teenager.[1] He trained in veterinary medicine and surgery, immunochemistry and immunology at the University of Sydney and in DNA technology at Stanford University. After doctoral studies at Melbourne's Walter and Eliza Hall Institute of Medical Research and the University of Sydney, he joined the faculty of the Stanford University Medical School and the Howard Hughes Medical Institute in 1990.[2] There he established the concept of multiple immune tolerance checkpoints, a framework now widely used in cancer treatment with "checkpoint inhibitors", and revealed the function of key genes in these checkpoints.[3]

In 1997 Goodnow joined the faculty at the Australian National University as Professor and Founding Director of the Medical Genome Centre, leading its development into a major national research facility, the Australian Phenomics Facility. In 2015 he joined the Garvan Institute of Medical Research as Deputy Director to translate genomic DNA sequence analysis of the human immune system into understanding the cause of immune disorders and developing more effective, personalised treatments.[2] During this period Goodnow oversaw the development of the Garvan-Weizmann Centre for Cellular Genomics in partnership with the Weizmann Institute of Science in Israel,[4][5] the only multidisciplinary centre of its kind in the southern hemisphere as well as playing a key role in the development of the Clinical Immunogenomics Research Consortium Australia (CIRCA).[6] In May 2018, Goodnow was named Executive Director of the Garvan Institute.[7]

Academic History

1979-84: Training in Veterinary Medicine and Surgery, Faculty of Veterinary Science, University of Sydney

1983: B.Sc.Vet research, "Cellular and Molecular Studies of Kappa Myeloma Antigen", Clinical Immunology Research Centre, University of Sydney, with Dr. R.L. Raison

1984: Graduated, University of Sydney, B.V.Sc. Hons I, and B.Sc.(Vet) Hons I and University Medal

1985: Visiting Student and Research Assistant in the laboratory of Dr. Mark M. Davis, Dept. of Medical Microbiology, Stanford University Medical School

1985: National Health and Medical Research Council Biomedical Scholar, Ph.D. research, "A transgenic mouse model for self-tolerance in B lymphocytes", Walter and Eliza Hall Institute, with Professor Gustav JV Nossal

1986-89: NHMRC Biomedical Scholar, Ph.D. research, "A transgenic mouse model for self-tolerance in B lymphocytes", Clinical Immunology Research Centre, University of Sydney, with Associate Professor Ronald J. Trent and Professor Antony Basten

1989-90: Medical Foundation Postdoctoral Fellow, Clinical Immunology Research Centre, University of Sydney, with Professor Antony Basten

1990-97: Assistant Investigator, Howard Hughes Medical Institute & Assistant Professor of Microbiology and Immunology, Stanford University Medical School

1992-95: Searle Scholar

1997: Professor, Director of Medical Genome Centre, Australian Cancer Research Foundation Genetics Laboratory, The John Curtin School of Medical Research, The Australian National University

2007-2014: Professor and Head of the Division of Genetics and Immunology, The John Curtin School of Medical Research, The Australian National University

2014–Present: Conjoint Professor, St Vincent's Clinical School, Faculty of Medicine, UNSW

Industry

Goodnow has served:

  • On the scientific advisory board of Illumina, a genetic analysis technology company; and
  • As founder and chief scientific officer for Phenomix Corp, a private biotechnology company.

Honours

Other Interests

Goodnow is well known for leading a 1980 expedition to Indonesia's remote Mentawai Islands of the coast of Sumatra, discovering the now-famous surf breaks and a wave that is today considered one of the world's best, Macaronis.[19][20]

External
gollark: Design a custom one which is subtly incompatible with all others, that never fails.
gollark: Replace the USB ports with I²C ports. What could possibly go wrong.
gollark: Is there much of a reason to not use USB for those? Implementation complexity?
gollark: My laptop seems to have its fingerprint scanner on USB.
gollark: I *think* some touchpads are I2C-connected?

References
  1. "ANU Spaces - Christopher Goodnow". ANU. 6 November 2014. Retrieved 29 June 2018.
  2. "Garvan welcomes Professor Chris Goodnow as Deputy Director | Garvan Institute of Medical Research". www.garvan.org.au. Retrieved 29 June 2018.
  3. Goodnow, Christopher C.; Cyster, Jason G.; Hartley, Suzanne B.; Bell, Sarah E.; Cooke, Michael P.; Healy, James I.; Akkaraju, Srinivas; Rathmell, Jeffrey C.; Pogue, Sarah L.; Shokat, Kevan P. (1 January 1995). Self-Tolerance Checkpoints in B Lymphocyte Development. Advances in Immunology. 59. pp. 279–368. doi:10.1016/S0065-2776(08)60633-1. ISBN 9780120224593. ISSN 0065-2776. PMID 7484462.
  4. "New Weizmann-Garvan centre established to study cellular genomics | WeizmannCompass". WeizmannCompass. Retrieved 29 June 2018.
  5. "Baird's big deals - The Australian Jewish News". The Australian Jewish News. 14 April 2016. Retrieved 29 June 2018.
  6. "Clinical Immunogenomics Research Consortium Australia - CIRCA | Garvan Institute of Medical Research". www.garvan.org.au. Retrieved 29 June 2018.
  7. "Visionary researcher Chris Goodnow to take the helm at Garvan Institute | Garvan Institute of Medical Research". Garvan Institute of Medical Research. Retrieved 29 June 2018.
  8. "Australian Honours". honours.pmc.gov.au. Retrieved 19 June 2018.
  9. "Gottschalk Medal | Australian Academy of Science". www.science.org.au. Retrieved 19 June 2018.
  10. "Professor Chris Goodnow | Australian Academy of Science". www.science.org.au. Retrieved 19 June 2018.
  11. ANU medical researcher wins national award, 2005-06-10, www.bio-medicine.org, accessed 2009-05-20
  12. "AAI Newsletter" (PDF). AAI. The American Association of Immunologists. October 2013.
  13. "Ramaciotti Awards & Recipients | Perpetual | Perpetual". www.perpetual.com.au. Retrieved 19 June 2018.
  14. ANU immunology pioneer elected to The Royal Society, Australian National University, 2009-05-15, accessed 2009-05-20
  15. "The Burnet Oration". www.immunology.org.au. Retrieved 19 June 2018.
  16. "Australia Fellowships Outcome" (PDF). NHMRC. Archived from the original (PDF) on 14 February 2014. Retrieved 19 June 2018.
  17. "Previous Winners | GSK Australia". Archived from the original on 19 June 2018. Retrieved 19 June 2018.
  18. http://www.nasonline.org, National Academy of Sciences -. "Christopher Goodnow". www.nasonline.org. Retrieved 19 June 2018.
  19. "Finding Macaronis: Part 1 | Swellnet". www.swellnet.com. Retrieved 29 June 2018.
  20. "Canberra Close Up: Professor Chris Goodnow". www.abc.net.au. 7 November 2012. Retrieved 29 June 2018.
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