Carotenoid isomerooxygenase
Carotenoid isomerooxygenase (EC 1.13.11.65, ninaB (gene)) is an enzyme with systematic name zeaxanthin:oxygen 15,15'-oxidoreductase (bond-cleaving, cis-isomerizing).[1] This enzyme catalyses the following chemical reaction
- zeaxanthin + O2 (3R)-11-cis-3-hydroxyretinal + (3R)-all-trans-3-hydroxyretinal
| Carotenoid isomerooxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.13.11.65 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The enzyme from the moth Galleria mellonella and the fruit fly Drosophila melanogaster takes part in the synthesis of retinal .
References
- Oberhauser V, Voolstra O, Bangert A, von Lintig J, Vogt K (December 2008). "NinaB combines carotenoid oxygenase and retinoid isomerase activity in a single polypeptide". Proceedings of the National Academy of Sciences of the United States of America. 105 (48): 19000–5. doi:10.1073/pnas.0807805105. PMC 2596218. PMID 19020100.
External links
- Carotenoid+isomerooxygenase at the US National Library of Medicine Medical Subject Headings (MeSH)
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