C8 complex
High Resolution Crystal Structure of Human Complement Component 8
| complement component 8, alpha polypeptide | |
|---|---|
| Identifiers | |
| Symbol | C8A |
| NCBI gene | 731 |
| HGNC | 1352 |
| OMIM | 120950 |
| RefSeq | NM_000562 |
| UniProt | P07357 |
| Other data | |
| Locus | Chr. 1 p36.2-22.1 |
| complement component 8, beta polypeptide | |
|---|---|
| Identifiers | |
| Symbol | C8B |
| NCBI gene | 732 |
| HGNC | 1353 |
| OMIM | 1209660 |
| RefSeq | NM_000066 |
| UniProt | P073o58 |
| Other data | |
| Locus | Chr. 1 p36.2-22.1 |
| complement component 8, gamma polypeptide | |
|---|---|
| Identifiers | |
| Symbol | C8G |
| NCBI gene | 733 |
| HGNC | 1354 |
| OMIM | 120930 |
| RefSeq | NM_000606 |
| UniProt | P07360 |
| Other data | |
| Locus | Chr. 9 q34.3 |
Membrane attack complex. Some labels are in Polish.
Structure
C8 is a heterotrimer; it consists of three different subunits. These are called C8 alpha, beta and gamma chains, encoded by the genes C8A, C8B and C8G respectively.
gollark: Mining turtles aren't *that* cheap.
gollark: Now that I have automining going, GTech will begin selling iron and gold ingots at 0.5KST and 1.5KST respectively.
gollark: This is ridiculous. We should all get them or nobody should.
gollark: Can you 3D-print some arms instead of weapons?
gollark: Bloodmoon == Lunar eclipse != solar eclipse
References
1.J Biol Chem. 2011 May 20;286(20):17585-92. Epub 2011 Mar 25. Figure created in Pymol
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.