Almagate

Almagate (trade name Almax) is an aluminium- and magnesium-containing antacid. It was first described in 1984.[1][2]

Almagate

Clinical data
AHFS/Drugs.com	International Drug Names
Routes of administration	Oral
ATC code	A02AD03 (WHO)
Identifiers
CAS Number	66827-12-1
PubChem CID	71749
ChemSpider	64792^Y
UNII	568Z59H7ZJ
KEGG	D02821^Y
CompTox Dashboard (EPA)	DTXSID30216935
Chemical and physical data
Formula	Al2Mg6(OH)14(CO3)2 · 4 H2O
Molar mass	314.99 g/mol
3D model (JSmol)	Interactive image
SMILES [Al+3].[Mg+2].[Mg+2].[Mg+2].[OH-].[OH-].[OH-].[O-]C([O-])=O.[OH-].[OH-].[OH-].[OH-].O.O
InChI InChI=1S/CH2O3.Al.3Mg.9H2O/c2-1(3)4;;;;;;;;;;;;;/h(H2,2,3,4);;;;;9*1H2/q;+3;3*+2;;;;;;;;;/p-9^Y Key:MTEOMEWVDVPTNN-UHFFFAOYSA-E^Y
(verify)

Adverse effects

Almagate is well tolerated. In a clinical trial, the most common adverse effects were diarrhea and nausea.[3]

References

1. Moragues J, Beneyto JE, Fábregas JL, Spickett RG (1984). "Characterization of a new crystalline synthetic gastric antacid, almagate" (Free full text). Arzneimittel-Forschung. 34 (10A): 1346–9. PMID 6548918.
2. Beneyto JE, Fábregas JL, Moragues J, Spickett RG (1984). "Evaluation of a new antacid, almagate" (Free full text). Arzneimittel-Forschung. 34 (10A): 1350–4. PMID 6439224.
3. Suau A, Dominguez Martin A, Ferrando Cucarella J, Juncosa Iglesias L, Muñoz Benitez J, Nieto Calvet M, et al. (1984). "Treatment of gastric pyrosis with almagate in patients with and without endoscopically demonstrable duodenal ulcer. A multicentre clinical trial" (Free full text). Arzneimittel-Forschung. 34 (10A): 1380–3. PMID 6548926.