α-Acetyldigoxin

α-Acetyldigoxin is a cardiac glycoside. It is an acetyl derivative of digoxin and an isomer of β-acetyldigoxin. It increases the contractility of the heart by its positive inotropic effect on cardiac muscle. The effects of α-acetyldigoxin begin 3–4 hours after administration, and maximize after 6–8 hours. It is prescribed for congestive chronic cardiac failure class II, III and IV.

α-Acetyldigoxin
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Oral
ATC code
Pharmacokinetic data
Bioavailability90%(Oral)
Protein binding20–30%
Elimination half-life40h
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.024.414
Chemical and physical data
FormulaC43H66O15
Molar mass822.986 g·mol−1
3D model (JSmol)
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