Hymecromone

Hymecromone (4-methylumbelliferone) is a drug used in bile therapy. It is used as choleretic and antispasmodic drugs and as a standard for the fluorometric determination of enzyme activity. [1]

Hymecromone

Clinical data
Other names	4-Methylumbelliferone
AHFS/Drugs.com	International Drug Names
ATC code	A05AX02 (WHO)
Identifiers
IUPAC name 7-Hydroxy-4-methylchromen-2-one
CAS Number	90-33-5^Y
PubChem CID	5280567
DrugBank	DB07118^Y
ChemSpider	4444190^Y
UNII	3T5NG4Q468
KEGG	D00170^Y
ChEBI	CHEBI:17224^Y
ChEMBL	ChEMBL12208^Y
CompTox Dashboard (EPA)	DTXSID8025670
ECHA InfoCard	100.001.806
Chemical and physical data
Formula	C10H8O3
Molar mass	176.171 g·mol^−1
3D model (JSmol)	Interactive image
SMILES CC1=CC(=O)OC2=C1C=CC(=C2)O
InChI InChI=1S/C10H8O3/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9/h2-5,11H,1H3^Y Key:HSHNITRMYYLLCV-UHFFFAOYSA-N^Y
(verify)

Hymecromone is a crystalline solid with a melting point of 194–195 °C. It is soluble in methanol and glacial acetic acid.

See also

• Umbelliferone
• Coumarin

References

1. Yang, Yongsok, and Kozo Hamaguchi. "Hydrolysis of 4-methylumbelliferyl N-acetyl-chitotriosidase catalyzed by hen and turkey lysozymes: pH dependence of the kinetic constants." The Journal of Biochemistry 87.4 (1980): 1003-1014.