1,2-dihydroxynaphthalene dioxygenase

1,2-dihydroxynaphthalene dioxygenase (EC 1.13.11.56, 1,2-DHN dioxygenase, DHNDO, 1,2-dihydroxynaphthalene oxygenase, 1,2-dihydroxynaphthalene:oxygen oxidoreductase) is an enzyme with systematic name naphthalene-1,2-diol:oxygen oxidoreductase.[1][2][3] This enzyme catalyses the following chemical reaction

naphthalene-1,2-diol + O2 2-hydroxy-2H-chromene-2-carboxylate
1,2-dihydroxynaphthalene dioxygenase
1,2-dihydroxynaphthalene dioxygenase oktamer, Pseudomonas
Identifiers
EC number1.13.11.56
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme is involved in naphthalene degradation.

References

  1. Kuhm AE, Stolz A, Ngai KL, Knackmuss HJ (June 1991). "Purification and characterization of a 1,2-dihydroxynaphthalene dioxygenase from a bacterium that degrades naphthalenesulfonic acids". Journal of Bacteriology. 173 (12): 3795–802. PMC 208010. PMID 2050635.
  2. Keck A, Conradt D, Mahler A, Stolz A, Mattes R, Klein J (July 2006). "Identification and functional analysis of the genes for naphthalenesulfonate catabolism by Sphingomonas xenophaga BN6". Microbiology. 152 (Pt 7): 1929–40. doi:10.1099/mic.0.28783-0. PMID 16804169.
  3. Patel TR, Barnsley EA (August 1980). "Naphthalene metabolism by pseudomonads: purification and properties of 1,2-dihydroxynaphthalene oxygenase". Journal of Bacteriology. 143 (2): 668–73. PMC 294337. PMID 7204331.
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