Systems Center Configuration Manager is a product by Microsoft that is used to manage the Configuration of multiple Windows-based systems.
SCCM is a Microsoft product that allows the management and deployment of system configuration for Windows-based systems. The most recent version, SCCM 2012 forms part of Microsoft's System Center 2012 software, which aims to help enterprises manage their ITIL practices more effectively.
Functionally, SCCM supports the deployment and configuration of software, update/patch management, AV management and reporting across an estate of Windows-based servers and workstations. It also tightly integrates with other Microsoft server technologies, such as Active Directory.