NetScaler is an application delivery controller (ADC) and load balancing solution developed, sold and supported by Citrix. NetScaler operates in a similar market as F5 and other leading load balancer/ADC solutions and comes in both physical hardware (MPX/SDX) and virtualized forms (VPX/SDX). NetScaler operates at OSI Layer 4-7 in general, though it does have some Layer 2/3 functionality.
As well as the traditional load balancing role, NetScaler also provides content switching, HTTP rewrites/manipulation, data compression, content caching, hardware based SSL acceleration (not VPX), application flow visibility and an application firewall.
The underlying OS of a NetScaler is FreeBSD based (6.3 currently) with a completely customized kernel, TCP/IP stack etc. running on commodity Intel x86 hardware. SSL acceleration is provided by cards (usually Cavium based).
Virtualized versions of NetScaler can be run on the SDX platform to take advantage of SSL acceleration, otherwise it is simply done in software. The official site can be found here: