Oleschri's explination is highly accurate.
One MS Support explanation was this a few days ago:
"After internal analysis and working with partners, we believe we’ve identified the root cause as a problem with how Adobe is using our registry key in IE, resulting in Adobe behaving as if it is blocked or not installed even though it is. The problem has been reported, and should be addressed in the next quarterly update of the Adobe PDF product. SCEP exposes the issue by activating the IE plug in scan functionality, but does not cause the issue. This also explains why we are not seeing similar issues with other IE plug ins."
There is no solution which is completely adequate. Short term solutions include including running a group policy client side preference to delete the Adobe CLSID key every so often if found, or modifying a IE shortcut to delete the CLSID before launching. Disabling Malware scanning in IE11, either per client or Group policy setting, via Internet Security Zone Settings, "Run Antimalware Software on ActiveX controls" is far from a wise choice I think most would agree.
Completely not recommended
GP location for setting is: "Administrative Templates\Windows Components\Internet Explorer\Internet Control Panel\Security Page\Internet Zone\"Don't run antimalware programs against ActiveX controls"
Adobe Resolved Issue
Fortunately, Adobe released v 11.0.14 on January 12th, 2016 which resolves this issue. As well, Adobe Reader DC, of the same release, date does not have this issue as well.
http://www.adobe.com/devnet-docs/acrobatetk/tools/ReleaseNotes/11/11.0.14.html
Here is a little VB script you can make a shortcut out of and deploy. This will delete the Adobe Reader CSLID then launch IE and go to Google.
Set WshShell = WScript.CreateObject("WScript.Shell")
On Error Resume Next
Key = "HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\Ext\Settings\{CA8A9780-280D-11CF-A24D-444553540000}"
WshShell.RegDelete Key & "\"
CreateObject("WScript.Shell").Run "https://www.google.com"
Wscript.quit
Regards