Any means of preventing data transfer between two systems. Typically this means isolating processes or VMs through sandboxing, or isolating network or physical resources through firewalls or air-gapping.
In security, "isolation" means preventing data transfer between two systems. Typically this means isolating processes or VMs through sandboxing, or isolating network or physical resources through firewalls or air-gapping.
Isolation can be two-way - as in a proper air-gap - or one-way - as in a host accessing a VM but not the other way around.