Zolantidine

Zolantidine is a brain-penetrating selective histamine H2 receptor (HRH2) antagonist developed by Smith, Kline & French, with the research code of SK&F 95282. It is a benzthiazole derivative with a 30-fold higher potency for H2 receptors than other peripheral and central receptors.[1]

Zolantidine
Clinical data
ATC code
  • None
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC22H27N3OS
Molar mass381.54 g·mol−1
3D model (JSmol)

References

  1. Calcutt CR, Ganellin CR, Griffiths R, Leigh BK, Maguire JP, Mitchell RC, et al. (January 1988). "Zolantidine (SK&F 95282) is a potent selective brain-penetrating histamine H2-receptor antagonist". British Journal of Pharmacology. 93 (1): 69–78. doi:10.1111/j.1476-5381.1988.tb11406.x. PMC 1853786. PMID 2894879.
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