MARVELD2

MARVEL domain-containing protein 2 is a protein that in humans is encoded by the MARVELD2 gene.[5][6]

MARVELD2
Identifiers
Aliases	MARVELD2, DFNB49, MARVD2, MRVLDC2, Tric, MARVEL domain containing 2
External IDs	OMIM: 610572 MGI: 2446166 HomoloGene: 27037 GeneCards: MARVELD2
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5q13.2 Start 69,415,065 bp[1] End 69,444,330 bp[1]
Gene location (Mouse) Chr. Chromosome 13 (mouse)[2] Band 13|13 D1 Start 100,595,957 bp[2] End 100,616,971 bp[2]
Gene ontology Molecular function • GO:0001948 protein binding Cellular component • cytoplasm • integral component of membrane • cell membrane • basolateral plasma membrane • apical plasma membrane • cytoplasmic vesicle • membrane • tricellular tight junction • bicellular tight junction • cell junction • paranodal junction • Schmidt-Lanterman incisure Biological process • establishment of endothelial barrier • cell-cell junction organization • sensory perception of sound • bicellular tight junction assembly Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	153562	218518
Ensembl	ENSG00000274671 ENSG00000152939	ENSMUSG00000021636
UniProt	Q8N4S9	Q3UZP0
RefSeq (mRNA)	NM_001038603 NM_001244734 NM_144724	NM_001038602 NM_178410
RefSeq (protein)	NP_001033692 NP_001231663	NP_001033691 NP_848497
Location (UCSC)	Chr 5: 69.42 – 69.44 Mb	Chr 13: 100.6 – 100.62 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. ENSG00000152939 GRCh38: Ensembl release 89: ENSG00000274671, ENSG00000152939 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000021636 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Riazuddin S, Ahmed ZM, Fanning AS, Lagziel A, Kitajiri S, Ramzan K, Khan SN, Chattaraj P, Friedman PL, Anderson JM, Belyantseva IA, Forge A, Riazuddin S, Friedman TB (Dec 2006). "Tricellulin is a tight-junction protein necessary for hearing". Am J Hum Genet. 79 (6): 1040–51. doi:10.1086/510022. PMC 1698716. PMID 17186462.
6. "Entrez Gene: MARVELD2 MARVEL domain containing 2".

Further reading

• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
• Ikenouchi J, Furuse M, Furuse K, et al. (2006). "Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells". J. Cell Biol. 171 (6): 939–45. doi:10.1083/jcb.200510043. PMC 2171318. PMID 16365161.
• Zhang Y, Wolf-Yadlin A, Ross PL, et al. (2005). "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules". Mol. Cell. Proteomics. 4 (9): 1240–50. doi:10.1074/mcp.M500089-MCP200. PMID 15951569.
• Ramzan K, Shaikh RS, Ahmad J, et al. (2005). "A new locus for nonsyndromic deafness DFNB49 maps to chromosome 5q12.3-q14.1". Hum. Genet. 116 (1–2): 17–22. doi:10.1007/s00439-004-1205-8. PMID 15538632.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.