Lorpiprazole

Lorpiprazole (INN) (brand name Normarex) is a marketed anxiolytic drug of the phenylpiperazine group.[1][2][3] It has been described as a serotonin antagonist and reuptake inhibitor (SARI) in the same group as trazodone, nefazodone, and etoperidone.[3]

Lorpiprazole

Clinical data
Routes of administration	Oral
ATC code	none
Legal status
Legal status	In general: uncontrolled
Identifiers
IUPAC name (5aR,8aS)-3-(2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}ethyl)-5,5a,6,7,8,8a-hexahydrocyclopenta[3,4]pyrrolo[2,1-c][1,2,4]triazole
CAS Number	108785-69-9
PubChem CID	3045380
ChemSpider	16736802
UNII	0M14O7T47Q
CompTox Dashboard (EPA)	DTXSID30883181
Chemical and physical data
Formula	C21H26F3N5
Molar mass	405.469 g·mol^−1
3D model (JSmol)	Interactive image
SMILES FC(F)(F)c1cc(ccc1)N5CCN(CCc4nnc2n4C[C@@H]3CCC[C@H]23)CC5

See also

• Acaprazine
• Enpiprazole
• Mepiprazole
• Tolpiprazole

References

1. Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 742–. ISBN 978-1-4757-2085-3.
2. Negwer M, Scharnow H (2001). Organic-Chemical Drugs and Their Synonyms. 1–6 (8th ed.). Weinheim: Wiley-VCH. ISBN 3-527-30247-6.
3. Fagiolini A, Comandini A, Catena Dell'Osso M, Kasper S (December 2012). "Rediscovering trazodone for the treatment of major depressive disorder". CNS Drugs. 26 (12): 1033–49. doi:10.1007/s40263-012-0010-5. PMC 3693429. PMID 23192413.