Bamifylline

Bamifylline is a drug of the xanthine chemical class which acts as a selective adenosine A1 receptor antagonist.[1][2]

Bamifylline
Names
IUPAC name
8-Benzyl-7-{2-[ethyl(2-hydroxyethyl)amino]ethyl}-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.116.522
UNII
Properties
C20H27N5O3
Molar mass 385.46008
Pharmacology
R03DA08 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

See also

References

  1. Tomai, F; Crea, F; Gaspardone, A; Versaci, F; De Paulis, R; Polisca, P; Chiariello, L; Gioffrè, PA (June 1996). "Effects of A1 adenosine receptor blockade by bamiphylline on ischaemic preconditioning during coronary angioplasty" (PDF). European Heart Journal. 17 (6): 846–53. doi:10.1093/oxfordjournals.eurheartj.a014965. PMID 8781823.
  2. Kofman, J; Grosclaude, M; Ouechni, MM; Perrin-Fayolle, M. "Comparative effects of bamifylline and theophylline on allergenic bronchospasm induced by the provocative inhalation test: double-blind cross-over study". Le Poumon et le Cœur (in French). 38 (3): 197–202. PMID 6752929.
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