Anasarca

Anasarca is a severe and generalized form of edema, with subcutaneous tissue swelling throughout the body.[1] Causes include liver failure,[2] kidney failure,[3] right-sided heart failure,[4] nephrotic syndrome,[5] protein-losing enteropathies,[6] severe protein deficiency,[7] and capillary leak syndrome.[8] Anasarca is often caused by a decreased oncotic pressure. It can also be caused by the administration of exogenous intravenous fluid. In Hb Barts, the high oxygen affinity results in poor oxygen delivery to peripheral tissues, resulting in anasarca.

Anasarca
A child with anasarca brought on by nephrosis associated with malaria
SpecialtyInternal medicine

References

  1. Kumar Vinay. Robbins and Cotran Pathologic Basis of Disease. 8th ed. p.112; Philadelphia: Saunders Elsevier, 2010. ISBN 978-0-8089-2402-9
  2. Kattula, Sri Rama Surya Tez; Avula, Akshay; Baradhi, Krishna M. (2020), "Anasarca", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID 30085555, retrieved 2020-07-02
  3. "Anasarca: Causes, Edema, and Treatment". Healthline. 2017-07-11. Retrieved 2020-07-02.
  4. "Anasarca - an overview | ScienceDirect Topics". sciencedirect.com. Retrieved 2020-07-02.
  5. "Nephrotic syndrome - Symptoms and causes". Mayo Clinic. Retrieved 2020-07-02.
  6. Yasuda, Jessica Lacy; Rufo, Paul A. (2018-02-26). "Protein-Losing Enteropathy in the Setting of Severe Iron Deficiency Anemia". Journal of Investigative Medicine High Impact Case Reports. 6. doi:10.1177/2324709618760078. ISSN 2324-7096. PMC 5833205. PMID 29511696.
  7. "Anasarca: Causes, treatment, and definition". medicalnewstoday.com. 2018-02-13. Retrieved 2020-07-02.
  8. Mehta, Ankita; Shah, Mansi (2016). "Case Report: Uncontrolled Anasarca: CapillaryLeak Syndrome". The Medicine Forum: Vol. 17 , Article 8. doi:10.29046/TMF.017.1.009. Retrieved 7 July 2020.
Classification
External resources


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