Zonadhesin

Zonadhesin is a protein that in humans is encoded by the ZAN gene. [5]

ZAN
Identifiers
AliasesZAN, zonadhesin (gene/pseudogene), zonadhesin
External IDsOMIM: 602372 MGI: 106656 HomoloGene: 124417 GeneCards: ZAN
Gene location (Human)
Chr.Chromosome 7 (human)[1]
Band7q22.1Start100,733,595 bp[1]
End100,797,797 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

7455

22635

Ensembl

ENSG00000146839

ENSMUSG00000079173

UniProt

Q9Y493

O88799

RefSeq (mRNA)

NM_011741

RefSeq (protein)

NP_003377
NP_775082

n/a

Location (UCSC)Chr 7: 100.73 – 100.8 MbChr 5: 137.38 – 137.48 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

This gene encodes a protein that functions in the species specificity of sperm adhesion to the egg zona pellucida. The encoded protein is located in the acrosome and may be involved in signaling or gamete recognition.

An allelic polymorphism in this gene results in both functional and frameshifted alleles; the reference genome represents the functional allele. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2015].

gollark: tio!debug
gollark: ```c#define let int#define var char#include <stdlib.h>#include <string.h>#include <stdio.h>let main() { var *j = 0; var* q = malloc(50005000); for (let i = 0; i < 10000; i++) { j = malloc(i); strcat(q, j); strcat(q, "apiobee"); free(j); q = j; } var* lyricLy_bad = malloc(3); printf("%s", j);}```
gollark: Oh, oops.
gollark: tio!debug
gollark: ```c#define let int#define var char#include <stdlib.h>#include <string.h>#include <stdio.h>let main() { var *j = 0; var* q = malloc(); for (let i = 0; i < 50005000; i++) { j = malloc(i); strcat(q, j); strcat(q, "apiobee"); free(j); q = j; } var* lyricLy_bad = malloc(3); printf("%s", j);}```

References
  1. GRCh38: Ensembl release 89: ENSG00000146839 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000079173 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Zonadhesin (gene/pseudogene)". Retrieved 2018-06-28.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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