Young's syndrome

Young's syndrome, also known as azoospermia sinopulmonary infections, sinusitis-infertility syndrome and Barry-Perkins-Young syndrome, is a rare condition that encompasses a combination of syndromes such as bronchiectasis, rhinosinusitis and reduced male fertility.[1][2][3] In individuals with this syndrome the functioning of the lungs is usually normal but the mucus is abnormally viscous. The reduced fertility ([obstructive [azoospermia]]) is due to functional obstruction of sperm transport down the genital tract at the epididymis, where the sperm is found in viscous, lipid-rich fluid.[3][4] The syndrome was named after Donald Young,[5] the urologist who first made observations of the clinical signs of the syndrome in 1972.[6]

Young's syndrome
Young's syndrome is inherited in an autosomal recessive manner

See also

• Infertility
• Cystic fibrosis

References

1. Handelsman DJ, Conway AJ, Boylan LM, Turtle JR (January 1984). "Young's syndrome. Obstructive azoospermia and chronic sinopulmonary infections". N. Engl. J. Med. 310 (1): 3–9. doi:10.1056/NEJM198401053100102. PMID 6689737.
2. Young syndrome at NIH's Office of Rare Diseases
3. Young's syndrome - General Practice Notebook
4. Definition: Young syndrome from Online Medical Dictionary
5. Young, M (January 2003). "Obituary of Donald Herron Young". BMJ. 326 (7382): 226. doi:10.1136/bmj.326.7382.226/g. PMC 1125087.
6. Online Mendelian Inheritance in Man (OMIM): Young syndrome - 279000

• Lau KY, Lieberman J (June 1986). "Young's syndrome. An association between male sterility and bronchiectasis". West. J. Med. 144 (6): 744–6. PMC 1306774. PMID 3727536.

External links

Classification	D ICD-10: Majorminor.LinkGroup ICD-9-CM: xxx OMIM: 279000 MeSH: C536718 DiseasesDB: 14241
External resources	Orphanet: 3471