Withania coagulans
Withania coagulans (Hindi: Paneer phool पनीरफूल, Sanskrit: Rishyagandha) is a plant in the Solanaceae or nightshade family, native to Afghanistan, Pakistan and the Indian subcontinent.[2] Within the genus Withania, W. somnifera (Ashwagandha) and W. coagulans (Paneer booti/Ashutosh booti) are economically significant, and are cultivated in several regions for their use in Ayurveda.[3] It is claimed to help control diabetes.[4] The berries contain a rennet-like protease that can be used to clot milk for cheese production.[5][6] The plant is prone to leaf spot disease caused by Alternaria alternata.[7]
Withania coagulans | |
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Scientific classification ![]() | |
Kingdom: | Plantae |
Clade: | Tracheophytes |
Clade: | Angiosperms |
Clade: | Eudicots |
Clade: | Asterids |
Order: | Solanales |
Family: | Solanaceae |
Genus: | Withania |
Species: | W. coagulans |
Binomial name | |
Withania coagulans (Stocks) Dunal | |
Synonyms[1] | |
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References
- "The Plant List: A Working List of All Plant Species". Retrieved 3 February 2015.
- "Withania coagulans". Germplasm Resources Information Network (GRIN). Agricultural Research Service (ARS), United States Department of Agriculture (USDA). Retrieved 3 February 2015.
- Mirjalili, M. H.; Moyano, E.; Bonfill, M.; Cusido, R. M.; Palazón, J. (2009). "Steroidal Lactones from Withania somnifera, an Ancient Plant for Novel Medicine". Molecules. 14 (7): 2373–2393. CiteSeerX 10.1.1.368.967. doi:10.3390/molecules14072373. PMC 6255378. PMID 19633611.
- Sampathkumar, Kaarunya; Riyajan, Siriporn; Tan, Chiew Kei; Demokritou, Philip; Chudapongse, Nuannoi; Loo, Say Chye Joachim (11 July 2019). "Small-Intestine-Specific Delivery of Antidiabetic Extracts from Withania coagulans Using Polysaccharide-Based Enteric-Coated Nanoparticles". ACS Omega. 4 (7): 12049–12057. doi:10.1021/acsomega.9b00823. PMC 6682046. PMID 31460318. Lay summary.
- Sheridan, Lea (March 1884). "A 'Rennet' Ferment Contained in the Seeds of Withania Coagulans". American Journal of Pharmacy. 56: 161. Bibcode:1883RSPS...36...55L.
- Beigomi M, Mohammadifar MA, Hashemi M, Rohani MG, Senthil K, Valizadeh M (December 2014). "Biochemical and rheological characterization of a protease from fruits of Withania coagulans with a milk-clotting activity". Food Science and Biotechnology. 23 (6): 1805–1813. doi:10.1007/s10068-014-0247-5. S2CID 84610288.
- Sharma, A; Singh, V; Singh, G; Pati, P. K (2013). "First Report of Leaf Spot Disease in Withania coagulans Caused by Alternaria alternata in India". Plant Disease. 97 (3): 420. doi:10.1094/PDIS-06-12-0559-PDN. PMID 30722353.
Further reading
- Upadhyay, B. N.; Gupta, Vandana (2011). "A clinical study on the effect of Rishyagandha (Withania coagulans) in the management of Prameha (Type II Diabetes Mellitus)". Ayu. 32 (4): 507–511. doi:10.4103/0974-8520.96124. PMC 3361926. PMID 22661845.
- Ojha, Shreesh; Alkaabi, Juma; Amir, Naheed; Sheikh, Azimullah; Agil, Ahmad; Fahim, Mohamed Abdelmonem; Adem, Abdu (2014). "Withania coagulans Fruit Extract Reduces Oxidative Stress and Inflammation in Kidneys of Streptozotocin-Induced Diabetic Rats". Oxidative Medicine and Cellular Longevity. 2014: 201436. doi:10.1155/2014/201436. PMC 4177777. PMID 25295146.
- White, Peter T.; Subramanian, Chitra; Motiwala, Hashim F.; Cohen, Mark S. (25 September 2016). "Natural Withanolides in the Treatment of Chronic Diseases". Anti-inflammatory Nutraceuticals and Chronic Diseases. Advances in Experimental Medicine and Biology. 928. pp. 329–373. doi:10.1007/978-3-319-41334-1_14. ISBN 978-3-319-41332-7. PMC 7121644. PMID 27671823.
- Palliyaguru, Dushani L.; Singh, Shivendra V.; Kensler, Thomas W. (2016). "Withania somnifera: from prevention to treatment of cancer". Molecular Nutrition & Food Research. 60 (6): 1342–1353. doi:10.1002/mnfr.201500756. PMC 4899165. PMID 26718910.
- Palliyaguru, Dushani L.; Chartoumpekis, Dionysios V.; Wakabayashi, Nobunao; Skoko, John J.; Yagishita, Yoko; Singh, Shivendra V.; Kensler, Thomas W. (December 2016). "Withaferin A induces Nrf2-dependent protection against liver injury: role of Keap1-independent mechanisms". Free Radical Biology & Medicine. 101: 116–128. doi:10.1016/j.freeradbiomed.2016.10.003. PMC 5154810. PMID 27717869.
- Chugh, Neha Arora; Bali, Shreya; Koul, Ashwani (2018). "Integration of botanicals in contemporary medicine: road blocks, checkpoints and go-ahead signals". Integrative Medicine Research. 7 (2): 109–125. doi:10.1016/j.imr.2018.03.005. PMC 6035497. PMID 29989061.
- Palliyaguru, Dushani L.; Chartoumpekis, Dionysios V.; Wakabayashi, Nobunao; Skoko, John J.; Yagishita, Yoko; Singh, Shivendra V.; Kensler, Thomas W. (December 2016). "Withaferin A induces Nrf2-dependent protection against liver injury: role of Keap1-independent mechanisms". Free Radical Biology & Medicine. 101: 116–128. doi:10.1016/j.freeradbiomed.2016.10.003. PMC 5154810. PMID 27717869.
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