Weber–Christian disease

Weber–Christian disease, is a cutaneous condition characterized by recurrent subcutaneous nodules that heal with depression of the overlying skin.[1]

Weber–Christian disease
Other namesRelapsing febrile nodular nonsuppurative panniculitis
SpecialtyRheumatology 

It is a type of panniculitis.[2] It is a rare disease seen in females 30–60 years of age. It is a recurring inflammation of fatty layers of tissue present beneath the skin. Clinical course is characterised by exacerbations and remissions. Lesions are bilaterally symmetrical and are usually seen in the lower legs.

Eponym

It is named after[3] Frederick Parkes Weber[4] and Henry Asbury Christian.[5]

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See also
  • Alpha-1 antitrypsin deficiency panniculitis
  • List of cutaneous conditions

References
  1. Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
  2. "Weber-Christian disease" at Dorland's Medical Dictionary
  3. Weber–Christian disease at Who Named It?
  4. Weber, F. Parkes (July 1925). "A CASE OF RELAPSING NON-SUPPURATIVE NODULAR PANNICULITIS, SHOWING PHAGOCYTOSIS OF SUBCUTANEOUS FAT-CELLS BY MACROPHAGES.*". British Journal of Dermatology. 37 (7): 301–311. doi:10.1111/j.1365-2133.1925.tb10003.x.
  5. Christian, Henry Asbury (1 September 1928). "Relapsing febrile nodular nonsuppurative panniculitis". Archives of Internal Medicine. Chicago. 42 (3): 338. doi:10.1001/archinte.1928.00020020026004.
Classification
External resources


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