Ulrich von Andrian

Ulrich von Andrian is a German Immunologist and professor of Microbiology and Immunobiology at Harvard University. He is best known for his work in the areas of leukocyte trafficking and the regulation of immune responses in lymph nodes, with a focus on how T-cell and B-cell-specific responses to antigen are initiated and how antigen is transported to the lymph nodes and presented by APCs.

Ulrich von Andrian
Born
Germany
Scientific career
FieldsMedicine, Neurology
InstitutionsHarvard University
Ludwig-Maximilians University Munich Germany

Education and academic career

Current Research at Harvard

von Andrian et al. have worked on uncovering the multi-step adhesion cascades that direct leukocyte subsets from the blood into various tissues in the body. His group has also characterized the dynamics of T-cell interactions with antigen-presenting dendritic cells and identified a critical role for macrophages at the lymph-tissue boundary. This work indicates that these cells participate in the adaptive immune response by “chelating” viral particles in the lymph, and then engaging B cells in the adjacent follicles to trigger B cell activation. His laboratory has also identified a subset of natural killer cells that acquires antigen-specific memory to haptens and viruses.

Awards and achievements

Inventions

"Bisphosphonates as novel adjuvants to enhance the adaptive immune response" [1]
"Novel target in NK cell mediated antigen specific memory responses"[2]

gollark: No.
gollark: I don't like it. We use a BT router with that "feature" at home and I cannot figure out how to turn it off and it *annoys me slightly*.
gollark: Self-driving cars should probably not be using the mobile/cell network just for communicating with nearby cars, since it adds extra latency and complexity over some direct P2P thing, and they can't really do things which rely on constant high-bandwidth networking to the internet generally, since they need to be able to not crash if they go into a tunnel or network dead zone or something.
gollark: My problem isn't *that* (5G apparently has improvements for more normal frequencies anyway), but that higher bandwidth and lower latency just... isn't that useful and worth the large amount of money for most phone users.
gollark: Personally I think 5G is pointless and overhyped, but eh.

See also

Pedram Hamrah

References
  1. http://otd.harvard.edu/technologies/tech.php?case=3845
  2. http://otd.harvard.edu/technologies/tech.php?case=3622
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