Trypanosoma equiperdum
Τrypanosoma equiperdum is a species of kinetoplastid parasites that causes Dourine or covering sickness in horses and other animals in the family equidae. T. equiperdum is the only trypanosome that is not spread by an insect vector.[1] There has been substantial controversy surrounding whether T. equiperdum should be considered a unique species, or a strain of T. evansi or T. brucei.[1][2] T. equiperdum is unique in that its kinetoplast, the network of connected rings that make up its mitochondrial DNA, consists of thousands of "minicircles" that are identical in sequence. [3]
| Τrypanosoma equiperdum | |
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_Trypanosoma_equiperdum.jpg) | |
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| Species: | T. equiperdum |
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| Trypanosoma equiperdum Døflein, 1901 | |
References
- Claes F, Buscher P, Touratier L, Goddeeris BM (2005). "Trypanosoma equiperdum: master of disguise or historical mistake?". Trends in Parasitology. 21 (7): 316–321. doi:10.1016/j.pt.2005.05.010.
- Lai, D.; Hashimi, Lun; Ayala, Lukes (2008). "Adaptations of Trypanosoma brucei to gradual loss of kinetoplast DNA: Trypanosoma equiperdum and Trypanosoma evansi are petite mutants of T. brucei". Proc Natl Acad Sci USA. 105 (6): 1999–2004. doi:10.1073/pnas.0711799105. PMC 2538871. PMID 18245376.
- Shapiro, Theresa (1993). "Kinetoplast DNA maxicircles: networks within networks". Proceedings of the National Academy of Sciences. 90 (16): 7809–7813. doi:10.1073/pnas.90.16.7809. PMC 47232. PMID 8395055.
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