TMX1

Thioredoxin-related transmembrane protein 1 is a protein that in humans is encoded by the TMX1 gene.[4][5]

TMX1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1X5E
Identifiers
Aliases	TMX1, PDIA11, TMX, TXNDC, TXNDC1, thioredoxin related transmembrane protein 1
External IDs	OMIM: 610527 MGI: 1919986 HomoloGene: 12482 GeneCards: TMX1
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q22.1 Start 51,240,162 bp[1] End 51,257,655 bp[1]
Gene ontology Molecular function • disulfide oxidoreductase activity • protein disulfide isomerase activity Cellular component • integral component of membrane • membrane • endoplasmic reticulum membrane • endoplasmic reticulum Biological process • protein folding • oxidation-reduction process • response to endoplasmic reticulum stress • cell redox homeostasis Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	81542	72736
Ensembl	ENSG00000139921	n/a
UniProt	Q9H3N1	Q8VBT0
RefSeq (mRNA)	NM_030755	NM_028339
RefSeq (protein)	NP_110382	NP_082615
Location (UCSC)	Chr 14: 51.24 – 51.26 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000139921 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. Matsuo Y, Akiyama N, Nakamura H, Yodoi J, Noda M, Kizaka-Kondoh S (Mar 2001). "Identification of a novel thioredoxin-related transmembrane protein" (PDF). J Biol Chem. 276 (13): 10032–8. doi:10.1074/jbc.M011037200. PMID 11152479.
5. "Entrez Gene: TXNDC1 thioredoxin domain containing 1".

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Heilig R, Eckenberg R, Petit JL, et al. (2003). "The DNA sequence and analysis of human chromosome 14". Nature. 421 (6923): 601–7. doi:10.1038/nature01348. PMID 12508121.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.