Sodium ferric gluconate complex

Sodium ferric gluconate complex, sold under the brand name Ferrlecit, is an intravenously administered iron medication for the treatment of iron deficiency anemia in adults and in children aged six years and older with chronic kidney disease receiving hemodialysis who are receiving supplemental epoetin therapy.[2] The macromolecule has an apparent molecular weight of 289,000 – 440,000 Dalton.[3]

Sodium ferric gluconate complex

Clinical data
Trade names	Ferrlecit
AHFS/Drugs.com	Monograph
MedlinePlus	a614030
License data	US DailyMed: Ferrlecit
Pregnancy category	US: B (No risk in non-human studies) [1]
Routes of administration	Intravenous (IV)
ATC code	B03AC (WHO)
Legal status
Legal status	US: ℞-only
Identifiers
CAS Number	34089-81-1
PubChem CID	76968835
DrugBank	DB09517
ChemSpider	34989638
UNII	CC9149U2QX
KEGG	D05859
CompTox Dashboard (EPA)	DTXSID80187686
Chemical and physical data
Formula	C66H121Fe2NaO65
Molar mass	2089.309 g·mol^−1
3D model (JSmol)	Interactive image
SMILES O[C@H]([C@@H](O)C(O[Na])=O)[C@H](O)[C@H](O)CO.O[C@H]([C@@H](O)C(O1)=O)[C@H](O)[C@H](O)CO.[Fe]1(OC(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)OC(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
InChI InChI=1S/5C12H22O11.C6H12O7.2Fe.Na.3O/c5*13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12;7-1-2(8)3(9)4(10)5(11)6(12)13;;;;;;/h5*4-11,13-20H,1-3H2;2-5,7-11H,1H2,(H,12,13);;;;;;/q;;;;;;2*+3;+1;3*-2/p-1/t5*4-,5-,6-,7-,8+,9-,10+,11-,12+;2-,3-,4+,5-;;;;;;/m111111....../s1 Key:MQBDAEHWGRMADS-XNHLMZCASA-M

The most common side effects in adults are nausea, vomiting and/or diarrhea, injection site reaction, hypotension, cramps, hypertension, dizziness, dyspnea, chest pain, leg cramps, and pain.[2] In children the most common side effects are hypotension, headache, hypertension, tachycardia and vomiting.[2]

References

1. "Sodium ferric gluconate complex Use During Pregnancy". Drugs.com. 16 December 2019. Retrieved 2 April 2020.
2. "Ferrlecit- sodium ferric gluconate complex injection". DailyMed. 25 September 2019. Retrieved 2 April 2020.
3. http://www.drugbank.ca/drugs/DB09517, retrieved 2020-Jun-21

External links

• "Sodium ferric gluconate complex". Drug Information Portal. U.S. National Library of Medicine.