Schnyder crystalline corneal dystrophy
Schnyder crystalline corneal dystrophy (SCD) is a rare form of corneal dystrophy. It is caused by heterozygous mutations in UBIAD1 gene.[1][2][3] Cells in the cornea accumulate cholesterol and phosopholipid deposits leading to the opacity, in severe cases requiring corneal transplants. Abnormal cholesterol metabolism has been noted in other cell types of affected patients (skin fibroblasts) suggesting that this may be a systemic disorder with clinical manifestations limited to the cornea.
Schnyder crystalline corneal dystrophy | |
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Other names | Crystalline stromal dystrophy, Schnyder crystalline dystrophy sine crystals, Hereditary crystalline stromal dystrophy of Schnyder , Schnyder's crystalline corneal dystrophy |
Schnyder corneal dystrophy. Crystalline opacities are evident in the central cornea (Courtesy Dr. G.N. Foulks) | |
Specialty | Ophthalmology |
Notes
- Orr et al, PLoS One (2007) vol 2, e685 doi:10.1371/journal.pone.0000685 PMID 17668063
- Yellore et al, Molec Vision (2007) vol 13, 1777-1782 PMID 17960116
- Weiss et al, IOVS (2007) vol 48, 5007-5012 doi:10.1167/iovs.07-0845 PMID 17962451
gollark: It's not particularly evil, since it will only be used to identify opting-in things.
gollark: But I skimmed a paper on it and apparently the randomization can be workarounded in some cases by sending RTS frames with the device's "hardcoded" MAC address and seeing if you get a CTS frame back.
gollark: This would have been doable by just checking the MAC address against a list several years ago, but evil beeoids also did this so now phones and such have randomization.
gollark: Well, for convoluted reasons, I want to detect known devices within wireless range.
gollark: Request to send.
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