SSC4D
Scavenger receptor cysteine rich family member with 4 domains is a protein that in humans is encoded by the SSC4D gene. [5]
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| Aliases | SSC4D, S4D-SRCRB, SRCRB-S4D, SRCRB4D, scavenger receptor cysteine rich family member with 4 domains | ||||||||||||||||||||||||
| External IDs | OMIM: 607639 MGI: 1924709 HomoloGene: 34137 GeneCards: SSC4D | ||||||||||||||||||||||||
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| Species | Human | Mouse | |||||||||||||||||||||||
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| Location (UCSC) | Chr 7: 76.39 – 76.41 Mb | Chr 5: 135.96 – 135.97 Mb | |||||||||||||||||||||||
| PubMed search | [3] | [4] | |||||||||||||||||||||||
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Function
The scavenger receptor cysteine-rich (SRCR) superfamily is an ancient and highly conserved group of cell surface and/or secreted proteins, some of which are involved in the development of the immune system and the regulation of both innate and adaptive immune responses. Group B SRCR domains usually contain 8 regularly spaced cysteines that give rise to a well-defined intradomain disulfide-bond pattern.
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References
- GRCh38: Ensembl release 89: ENSG00000146700 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000029699 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Entrez Gene: Scavenger receptor cysteine rich family member with 4 domains". Retrieved 2016-09-05.
Further reading
- Padilla O, Pujana MA, López-de la Iglesia A, Gimferrer I, Arman M, Vilà JM, Places L, Vives J, Estivill X, Lozano F (2002). "Cloning of S4D-SRCRB, a new soluble member of the group B scavenger receptor cysteine-rich family (SRCR-SF) mapping to human chromosome 7q11.23". Immunogenetics. 54 (9): 621–34. doi:10.1007/s00251-002-0507-z. PMID 12466895.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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