S-Adenosylmethioninamine

S-Adenosylmethioninamine (decarboxylated S-adenosyl methionine) is a substrate that is involved in the biosynthesis of polyamines including spermidine, spermine, and thermospermine.[1]

S-Adenosylmethioninamine

Names
IUPAC name 3-aminopropyl-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-methylsulfanium
Other names S-Adenosyl-(5′)-3-methylthiopropylamine, decarboxylated S-adenosyl methionine, (5-Deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium cation
Identifiers
CAS Number	22365-13-5^N
3D model (JSmol)	Interactive image
Abbreviations	dAdoMet, dc-SAM
ChEBI	CHEBI:15625^Y
ChemSpider	388529^N
KEGG	C01137^Y
PubChem CID	439415
InChI InChI=1S/C14H23N6O3S/c1-24(4-2-3-15)5-8-10(21)11(22)14(23-8)20-7-19-9-12(16)17-6-18-13(9)20/h6-8,10-11,14,21-22H,2-5,15H2,1H3,(H2,16,17,18)/q+1/t8-,10-,11-,14-,24?/m1/s1^N Key: ZUNBITIXDCPNSD-LSRJEVITSA-N^N InChI=1/C14H23N6O3S/c1-24(4-2-3-15)5-8-10(21)11(22)14(23-8)20-7-19-9-12(16)17-6-18-13(9)20/h6-8,10-11,14,21-22H,2-5,15H2,1H3,(H2,16,17,18)/q+1/t8-,10-,11-,14-,24?/m1/s1 Key: ZUNBITIXDCPNSD-LSRJEVITBK
SMILES C[S+](CCCN)C[C@@H]1[C@H]([C@H]([C@@H](O1)n2cnc3c2ncnc3N)O)O
Properties
Chemical formula	C14H23N6O3S^+
Molar mass	355.43582 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is ^YN ?)
Infobox references

See also

• Adenosylmethionine decarboxylase
• Spermidine synthase
• Spermine synthase
• Thermospermine synthase (ACAULIS5)

References

1. Takahashi, Taku; Kakehi, Jun-Ichi (2009-10-13). "Polyamines: Ubiquitous polycations with unique roles in growth and stress responses". Annals of Botany. 105 (1): 1–6. doi:10.1093/aob/mcp259. PMC 2794062. PMID 19828463.