Rickettsia rpsL leader

The Rickettsia rpsL leader is a putative attenuator element identified by bioinformatics within bacteria of the α-proteobacterial genus Rickettsia.[1] It is located upstream of the operon encoding ribosomal proteins S12 and S7 (rpsL and rpsG genes respectively), and presents a Rho-independent terminator at the 3' end. This RNA is presumed to operate as a non-coding ribosomal protein leader potentially interacting with the S12 or S7 proteins, encoded by the operon. The motif might be related to other rpsL leaders, such as that from Pseudomonas.[1]

Rickettsia rpsL leader
Conserved secondary structure of Rickettsia rpsL leader showing the fraction of canonical base pairs
Identifiers
SymbolrpsL_ricks
RfamRF01774
Other data
RNA typeCis-reg; leader
Domain(s)Rickettsia
PDB structuresPDBe

References
  1. Naville M, Gautheret D (2010). "Premature terminator analysis sheds light on a hidden world of bacterial transcriptional attenuation". Genome Biology. 11 (9): R97. doi:10.1186/gb-2010-11-9-r97. PMC 2965389. PMID 20920266.
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