Retusin (isoflavone)

Retusin is an O-methylated isoflavone, a type of flavonoid. It can be found in Fabaceae species like Dipteryx odorata,[1][2] in Dalbergia retusa[3] and in Millettia nitida.[4] It can also be found in Maackia amurensis cell cultures.[5]

Not to be confused with retusin (flavonol).

Retusin

Names
IUPAC name 7,8-dihydroxy-3-(4-methoxyphenyl)chromen-4-one
Other names 7,8-dihydroxy-4′-methoxyisoflavone
Identifiers
CAS Number	37816-19-6^Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL1290231^N
ChemSpider	4587189^N
PubChem CID	5481240
CompTox Dashboard (EPA)	DTXSID30420499
InChI InChI=1S/C16H12O5/c1-20-10-4-2-9(3-5-10)12-8-21-16-11(14(12)18)6-7-13(17)15(16)19/h2-8,17,19H,1H3^N Key: DLXIJJURUIXRFK-UHFFFAOYSA-N^N InChI=1/C16H12O5/c1-20-10-4-2-9(3-5-10)12-8-21-16-11(14(12)18)6-7-13(17)15(16)19/h2-8,17,19H,1H3 Key: DLXIJJURUIXRFK-UHFFFAOYAG
SMILES COC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3O)O
Properties
Chemical formula	C16H12O5
Molar mass	284.26 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is ^YN ?)
Infobox references

References

1. Isoflavones from Dipteryx odorata. Teruo Hayashi and Ronald H. Thomson, Phytochemistry, Volume 13, Issue 9, September 1974, Pages 1943-1946
2. Microsomal metabolism of calycosin, formononetin and drug–drug interactions by dynamic microdialysis sampling and HPLC–DAD–MS analysis. Xiao-Dong Wen, Lian-Wen Qi, Bin Lia, Ping Li, Ling Yia, Ya-Qiong Wang, E-Hu Liu and Xiao-Lin Yang, Journal of Pharmaceutical and Biomedical Analysis, Volume 50, Issue 1, 15 August 2009, Pages 100-105
3. Retusin (Dalbergia) on kanaya.naist.jp/
4. Interactions between thrombin and natural products of Millettia nitita var. hirsutissima using capillary zone electrophoresis. Shuyu Zhang, Jun Cheng, Wenjing Chen, Xiaomei Ling, Yuying Zhao, Jie Feng, Cheng Xiang and Hong Liang, Journal of Chromatography B, Volume 877, Issue 32, 15 December 2009, pages 4107-4114, doi:10.1016/j.jchromb.2009.10.033
5. Isoflavonoid production by callus cultures of Maackia amurensis. S.A Fedoreyev, T.V Pokushalov, M.V Veselova, L.I Glebko, N.I Kulesh, T.I Muzarok, L.D Seletskaya, V.P Bulgakov and Yu.N Zhuravlev, Fitoterapia, 1 August 2000, Volume 71, Issue 4, Pages 365–372, doi:10.1016/S0367-326X(00)00129-5