Raoultella terrigena

Raoultella terrigena is a Gram-negative bacterial species of the genus Raoultella, previously classified in the genus Klebsiella[1]. It has primarily been isolated from soil and water samples,[2] but rarely from humans. Studies have estimated fewer than 1% of healthy people harbor this species.[3] This species has shown no connection with disease in humans despite expressing many of the virulence factors expressed by other Klebsiella species such as Klebsiella pneumoniae.[4]

Raoultella terrigena
Scientific classification
Kingdom:
Bacteria
Phylum:
Proteobacteria
Class:
Gammaproteobacteria
Order:
Enterobacterales
Family:
Enterobacteriaceae
Genus:
Raoultella
Species:
R. terrigena

Phylogenic comparisons between the 16s rRNA and rpoB genes of this and other Klebsiella species have suggested classification into a newer genus, Raoultella[1], a reclassification that has been adopted[5].

R. terrigena is considered a factor in melamine toxicity. In culture, R. terrigena was shown to convert melamine to cyanuric acid directly. Rats colonized by R. terrigena showed greater melamine-induced kidney damage compared to those not colonized.[6]

References
  1. Drancourt, M; Bollet, C; Carta, A; Rousselier, P (May 2001). "Phylogenetic analyses of Klebsiella species delineate Klebsiella and Raoultella gen. nov., with description of Raoultella ornithinolytica comb. nov., Raoultella terrigena comb. nov. and Raoultella planticola comb. nov". International Journal of Systematic and Evolutionary Microbiology. 51 (Pt 3): 925–32. doi:10.1099/00207713-51-3-925. PMID 11411716.
  2. Izard, D.; Ferragut, C.; Gavini, F.; Kersters, K.; de Ley, J.; Leclerc, H. (1 April 1981). "Klebsiella terrigena, a new species from soil and water". International Journal of Systematic Bacteriology. 31 (2): 116–127. doi:10.1099/00207713-31-2-116.
  3. Neergaard, Lauran. "Study Examines Why Most Survived China's Melamine Scare". Food Manufacturing News. Food Manufacturing. Retrieved 22 February 2013.
  4. Podschun, R.; Fischer, A.; Ullmann, U. (Aug 2000). "Characterization of Klebsiella terrigena strains from humans: haemagglutinins, serum resistance, siderophore synthesis, and serotypes". Epidemiol Infect. 125 (1): 71–8. doi:10.1017/S0950268899004124. PMC 2869571. PMID 11057961.
  5. J.P. Euzéby: List of Prokaryotic names with Standing in Nomenclature – integrated into the DSMZ’s Prokaryotic Nomenclature Up-to-date (PNU) database
  6. Zheng, X.; et al. (13 Feb 2013). "Melamine-induced renal toxicity is mediated by the gut microbiota". Science Translational Medicine. 5 (172): 172ra22. doi:10.1126/scitranslmed.3005114. PMID 23408055.


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