RNF39

RING finger protein 39 is a protein that in humans is encoded by the RNF39 gene.[4][5][6]

RNF39
Identifiers
Aliases	RNF39, HZF, HZFW, LIRF, ring finger protein 39, FAP216
External IDs	OMIM: 607524 MGI: 2156378 HomoloGene: 11891 GeneCards: RNF39
Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6p22.1 Start 30,070,266 bp[1] End 30,075,887 bp[1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • metal ion binding Cellular component • cytoplasm • cellular component Biological process • biological process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	80352	386454
Ensembl	ENSG00000230467 ENSG00000206500 ENSG00000204618 ENSG00000237733 ENSG00000227171 ENSG00000235022 ENSG00000236967 ENSG00000230332	n/a
UniProt	Q9H2S5	n/a
RefSeq (mRNA)	NM_170770 NM_025236 NM_170769	NM_001099632
RefSeq (protein)	NP_079512 NP_739575	n/a
Location (UCSC)	Chr 6: 30.07 – 30.08 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

This gene lies within the major histocompatibility complex class I region on chromosome 6. Studies of a similar rat protein suggest that this gene encodes a protein that plays a role in an early phase of synaptic plasticity. Alternative splicing results in three transcript variants encoding different isoforms.[6]

References

1. ENSG00000206500, ENSG00000204618, ENSG00000237733, ENSG00000227171, ENSG00000235022, ENSG00000236967, ENSG00000230332 GRCh38: Ensembl release 89: ENSG00000230467, ENSG00000206500, ENSG00000204618, ENSG00000237733, ENSG00000227171, ENSG00000235022, ENSG00000236967, ENSG00000230332 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. Coriton O, Lepourcelet M, Hampe A, Galibert F, Mosser J (Dec 2000). "Transcriptional analysis of the 69-kb sequence centromeric to HLA-J: a dense and complex structure of five genes". Mamm Genome. 11 (12): 1127–31. doi:10.1007/s003350010213. PMID 11130983.
5. Matsuo R, Asada A, Fujitani K, Inokuchi K (Nov 2001). "LIRF, a gene induced during hippocampal long-term potentiation as an immediate-early gene, encodes a novel RING finger protein". Biochem Biophys Res Commun. 289 (2): 479–84. doi:10.1006/bbrc.2001.5975. PMID 11716498.
6. "Entrez Gene: RNF39 ring finger protein 39".

Further reading

• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Orimo A, Yamagishi T, Tominaga N, et al. (2000). "Molecular cloning of testis-abundant finger Protein/Ring finger protein 23 (RNF23), a novel RING-B box-coiled coil-B30.2 protein on the class I region of the human MHC". Biochem. Biophys. Res. Commun. 276 (1): 45–51. doi:10.1006/bbrc.2000.3380. PMID 11006080.
• Hidaka M, Caruana G, Stanford WL, et al. (2000). "Gene trapping of two novel genes, Hzf and Hhl, expressed in hematopoietic cells". Mech. Dev. 90 (1): 3–15. doi:10.1016/S0925-4773(99)00234-8. PMID 10585558.
• Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.